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雑誌文献

臨床検査62巻8号

2018年08月発行

文献概要

今月の特集 女性のライフステージと臨床検査

閉経と糖代謝異常

著者: 佐藤麻子1

所属機関: 1東京女子医科大学臨床検査科

ページ範囲:P.905 - P.909

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●高齢女性の糖尿病有病率は高い.

●閉経によるホルモン変化が糖代謝に影響を与える可能性はあるが,明確なエビデンスはない.

●閉経期ホルモン療法(MHT)は,糖尿病新規発症リスクの低下や2型糖尿病女性の血糖コントロール改善に関与している.

●閉経後の女性は,定期的な糖代謝機能の検査を行うことが大切である.

参考文献

1)厚生労働省:平成28年 国民健康・栄養調査結果の概要(http://www.mhlw.go.jp/file/04-Houdouhappyou-10904750-Kenkoukyoku-Gantaisakukenkouzoushinka/kekkagaiyou_7.pdf)(最終アクセス:2018年6月11日)
2)DeFronzo RA, Ferrannini E: Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 14:173-194,1991
3)Yonezawa R, Wada T, Matsumoto N, et al: Central versus peripheral impact of estradiol on the impaired glucose metabolism in ovariectomized mice on a high-fat diet. Am J Physiol Endocrinol Metab 303:E445-E456,2012
4)笹岡利安,恒枝宏史,和田努:エストロゲンと糖代謝.糖尿病 51:829-832,2008
5)Mishra GD, Carrigan G, Brown WJ, et al:Short-term weight change and the incidence of diabetes in midlife: results from the Australian Longitudinal Study on Women's Health. Diabetes Care 30:1418-1424,2007
6)Brand JS, van der Schouw YT, Onland-Moret NC, et al:Age at menopause, reproductive life span, and type 2 diabetes risk: results from the EPIC-InterAct study. Diabetes Care 36:1012-1019,2013
7)Janssen I, Powell LH, Crawford S, et al:Menopause and the metabolic syndrome: the Study of Women's Health Across the Nation. Arch Intern Med 168:1568-1575,2008
8)Ceausu I, Shakir YA, Lidfeldt J, et al:The hysterectomized woman. Is she special? The women's health in the Lund area (WHILA) study. Maturitas 53:201-209,2006
9)Kanaya AM, Herrington D, Vittinghoff E, et al:Glycemic effects of postmenopausal hormone therapy: the Heart and Estrogen/progestin Replacement Study. A randomized, double-blind, placebo-controlled trial. Ann Intern Med 138:1-9,2003
10)de Lauzon-Guillain B, Fournier A, Fabre A, et al:Menopausal hormone therapy and new-onset diabetes in the French Etude Epidemiologique de Femmes de la Mutuelle Générale de l'Education Nationale (E3N) cohort. Diabetologia 52:2092-2100,2009
11)Bonds DE, Lasser N, Qi L, et al:The effect of conjugated equine oestrogen on diabetes incidence: the Women's Health Initiative randomised trial. Diabetologia 49:459-468,2006
12)Margolis KL, Bonds DE, Rodabough RJ, et al:Effect of oestrogen plus progestin on the incidence of diabetes in postmenopausal women: results from the Women's Health Initiative Hormone Trial. Diabetologia 47:1175-1187,2004
13)Andersson B, Mattsson LA, Hahn L, et al:Estrogen replacement therapy decreases hyperandrogenicity and improves glucose homeostasis and plasma lipids in postmenopausal women with noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 82:638-643,1997
14)Crespo CJ, Smit E, Snelling A, et al:Hormone replacement therapy and its relationship to lipid and glucose metabolism in diabetic and nondiabetic postmenopausal women: results from the Third National Health and Nutrition Examination Survey (NHANES III). Diabetes Care 25:1675-1680,2002
15)Salpeter SR, Walsh JM, Ormiston TM, et al:Meta-analysis: effect of hormone-replacement therapy on components of the metabolic syndrome in postmenopausal women. Diabetes Obes Metab 8:538-554,2006

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1367

印刷版ISSN:0485-1420

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