臨床検査64巻3号

2020年03月発行

今月の特集1 Clostridioides difficile感染症—近年の話題

Clostridioides difficile感染症と糞便微生物移植

著者： 水野慎大¹

所属機関： ¹医療法人社団焔やまと診療所

ページ範囲：P.238 - P.243

Point

●糞便微生物移植法（FMT）は，多様性が低下した患者の腸内細菌叢を健常人の腸内細菌叢に置換する治療法である．

●FMTの歴史は古いが，基礎医学的な研究の進展に伴って近年急速に普及している．

●FMTの有用性が立証されている疾患は，再発性（難治性）Clostridioides difficile感染症（CDI）のみである．

●FMTの安全性・簡便性を向上させるために，糞便バンクや，カプセル化した細菌カクテルの開発など，さまざまな試みが進められている．

参考文献

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