icon fsr

文献詳細

雑誌文献

臨床検査68巻2号

2024年02月発行

文献概要

今月の特集2 人工物感染症

人工関節周囲感染

著者: 沖中友秀1 的野多加志2

所属機関: 1飯塚病院感染症科 2佐賀大学感染制御部

ページ範囲:P.190 - P.196

文献購入ページに移動
Point

●人工関節置換術は患者の生活の質(QOL)向上が期待できる一方で,人工関節周囲感染(PJI)といった術後合併症の危険も潜んでいる.

●PJIは発症の時期によって“早期型”,“遅延型”,“晩期型”に分けられ,それぞれの症状や原因微生物が異なる.

●Parviziらが提唱しているPJIの診断基準は,高い感度と特異度を示し,人工関節感染の診断に有用である.

●治療の基本は抗菌薬治療と外科的ドレナージであり,外科的ドレナージはいくつかの戦術に分かれ,原因微生物によってアプローチや治療期間が異なる.

参考文献

1)Patel R:Periprosthetic Joint Infection. N Engl J Med 388:251-262,2023
2)Namba RS, Inacio MC, Paxton EW:Risk factors associated with deep surgical site infections after primary total knee arthroplasty: an analysis of 56,216 knees. J Bone Joint Surg Am 95:775-782,2013
3)Edwards JR, Peterson KD, Mu Y, et al:National Healthcare Safety Network (NHSN) report: data summary for 2006 through 2008, issued December 2009. Am J Infect Control 37:783-805,2009
4)Beam E, Osmon D:Prosthetic Joint Infection Update. Infect Dis Clin North Am 32:843-859,2018
5)Tai DBG, Patel R, Abdel MP, et al:Microbiology of hip and knee periprosthetic joint infections: a database study. Clin Microbiol Infect 28:255-259,2022
6)Berbari EF, Marculescu C, Sia I, et al:Culture-negative prosthetic joint infection. Clin Infect Dis 45:1113-1119,2007
7)Marigi EM, Bartels DW, Yoon JH, et al:Antibiotic Prophylaxis with Cefazolin Is Associated with Lower Shoulder Periprosthetic Joint Infection Rates Than Non-Cefazolin Alternatives. J Bone Joint Surg Am 104:872-880,2022
8)Osmon DR, Berbari EF, Berendt AR, et al:Diagnosis and management of prosthetic joint infection: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis 56:e1-e25,2013
9)Parvizi J, Tan TL, Goswami K, et al:The 2018 Definition of Periprosthetic Hip and Knee Infection: An Evidence-Based and Validated Criteria. J Arthroplasty 33:1309-1314.e2,2018
10)Shahi A, Parvizi J, Kazarian GS, et al:The Alpha-defensin Test for Periprosthetic Joint Infections Is Not Affected by Prior Antibiotic Administration. Clin Orthop Relat Res 474:1610-1615,2016
11)Klement MR, Siddiqi A, Rock JM, et al:Positive Blood Cultures in Periprosthetic Joint Infection Decrease Rate of Treatment Success. J Arthroplasty 33:200-204.e1,2018
12)Peel TN, Dylla BL, Hughes JG, et al:Improved Diagnosis of Prosthetic Joint Infection by Culturing Periprosthetic Tissue Specimens in Blood Culture Bottles. mBio 7:e01776-15,2016
13)Zhai Z, Li H, Qin A, et al:Meta-analysis of sonication fluid samples from prosthetic components for diagnosis of infection after total joint arthroplasty. J Clin Microbiol 52:1730-1736,2014
14)Trampuz A, Piper KE, Jacobson MJ, et al:Sonication of removed hip and knee prostheses for diagnosis of infection. N Engl J Med 357:654-663,2007
15)Frangiamore SJ, Gajewski ND, Saleh A, et al:α-Defensin Accuracy to Diagnose Periprosthetic Joint Infection-Best Available Test?. J Arthroplasty 31:456-460,2016
16)Liu GD, Yu HJ, Ou S, et al:Human beta-defensin-3 for the diagnosis of periprosthetic joint infection and loosening. Orthopedics 37:e384-e390,2014
17)Zimmerli W, Trampuz A, Ochsner PE:Prosthetic-joint infections. N Engl J Med 351:1645-1654,2004
18)Segreti J, Nelson JA, Trenholme GM:Prolonged suppressive antibiotic therapy for infected orthopedic prostheses. Clin Infect Dis 27:711-713,1998

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1367

印刷版ISSN:0485-1420

雑誌購入ページに移動
icon up
あなたは医療従事者ですか?