精神医学50巻9号

2008年09月発行

研究と報告

統合失調症のminor physical anomalies(MPAs)と家族歴の有無の検討

著者： 奥村匡敏¹ 岩谷潤¹ 山本眞弘¹ 正山勝¹ 上山栄子¹ 小瀬朝海¹ 辻富基美¹ 鵜飼聡¹ 篠崎和弘¹

所属機関： ¹和歌山県立医科大学神経精神医学教室

ページ範囲：P.873 - P.876

抄録

　2005年12月時点に国保日高総合病院精神神経科に入院していた統合失調症患者について，minor physical anomalies(MPAs)と家族歴の関係を検討した。MPAs総数は家族歴がない群に比べてある群のほうが多かった。MPAs下位項目では，眼間開離，耳介低位と長い第3趾が家族歴と有意な関連を示した。今回の結果より，MPAsが統合失調症の脆弱性因子となる可能性が示唆された。さらには，耳介低位，眼間開離と長い第3趾が統合失調症のハイリスク群の同定のための1つの指標となり得るのではないかと考えた。

参考文献

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