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文献概要

特集 統合失調症の予後改善に向けての新たな戦略

認知矯正療法による予後改善―NEARを中心に

著者: 最上多美子1 中込和幸2

所属機関: 1鳥取大学大学院医学系研究科臨床心理学専攻 2鳥取大学医学部脳神経医科学講座精神行動医学分野

ページ範囲:P.143 - P.149

はじめに

 認知矯正療法は認知機能障害を改善することで統合失調症の予後の改善を目指す心理社会的手法である。認知機能障害は前駆期から認められ,急性期に悪化するが安定期には顕著な改善は認められない。統合失調症のおよそ8割が認知機能障害を示し,その深刻さは健常者の平均と比較して1.5標準偏差ほど低いといわれるように顕著である。認知機能障害は社会機能,自立生活機能,就労機能と多方面にわたり影響を及ぼすことから,予後改善につながる重要な治療標的である。認知矯正療法はこれら機能の基盤になる注意,記憶,問題解決,処理速度などの認知機能を訓練する。認知矯正療法には複数の種類があるが,本稿ではNEAR(Neuropsychological and Educational Approach to Cognitive Rehabilitation)を中心に解説する。

参考文献

1) Birchwood M, Smith J, Cochrane R:The social functioning scale:The development and validation of a new scale of social adjustment for use in family intervention programmes with schizophrenic patients. Br J Psychiatry 157:853-859, 1990
2) Choi J, Fiszdon JM, Medalia A:Expectancy-value theory in persistence of learning effects in schizophrenia:Role of task value and perceived competency. Schizophr Bull 36:957-965, 2010
3) Choi J, Medalia A:Factors associated with a positive response to cognitive remediation in a community psychiatric sample. Psychiatr Serv 56:602-604, 2005
4) Green MF, Nuechterlin KH, Gold JM, et al:Approaching a consensus cognitive battery for clinical trials in schizophrenia:The NIMH-MATRICS conference to select cognitive domains and test. Biol Psychiatr 56:301-330, 2004
5) Hodge MA, Siciliano PW, Moss B, et al:A randomized controlled trial of cognitive remediation in schizophrenia. Schizophr Bull 36:419-427, 2010
6) Keefe RSE, Harvey PD, Goldberg TE, et al:Norms and standardization of the Brief Assessment of Cognition in Schizophrenia. Schizophr Res 102:108-115, 2008
7) Keefe RSE, Poe M, Walker TM, et al:The Schizophrenia Cognition Rating Scale:An interview-based assessment and its relationship to cognition, real-world functioning, and functional capacity. Am J Psychiatry 163:426-432, 2006
8) Krabbendam L, Aleman A:Cognitive rehabilitation in schizophrenia:A quantitative analysis of controlled studies. Psychopharmacology 169:376-382, 2003
9) McGurk SR, Twamley EW, Sitzer DI:A meta-analysis of cognitive remediation in schizophrenia. Am J Psychiatry 164:1791-1802, 2007
10) Medalia A, Choi J:Cognitive remediation in schizophrenia. Neuropsychol Rev 19:353-364, 2009
11) Medalia A, Dorn H, Watras-Gans S:Treating problem-solving deficits on an acute care psychiatric inpatient unit. Psychiatr Res 97:70-88, 2000
12) Medalia A, Herlands T, Baginsky C:Rehab rounds:Cognitive remediation in supportive housing stetting. Psychiatr Serv 54:1219-1220, 2003
13) Medalia A, Revheim N, Casey M:Remediation of problem-solving skills in schizophrenia:Evidence of a persistent effect. Schizophr Res 57:165-171, 2002
14) Medalia A, Revheim N, Herlands T 著,中込和幸,最上多美子 訳:「精神疾患における認知機能障害の矯正法」臨床家マニュアル.星和書店,2008
15) Naismith SL, Redoblado-Hodge MA, Lewis SJG, et al:Cognitive training in affective disorders improves memory:A preliminary study using the NEAR approach:J Affect Disord, 2009, 121:258-262, 2010
16) Patterson TL, Goldman S, McKibbin C, et al:UCSD Performance-Based Skills Assessment:development of a new measure of everyday functioning for severely mentally ill adults. Schizophr Bull 27:235-245, 2010
17) Patterson TL, Moscona S, McKibbin CL, et al:Social skills performance assessment among older patients with schizophrenia. Schizophr Res 48:351-360, 2010
18) Revheim N, Kamnitzer D, Casey M, et al:Implementation of a cognitive rehabilitation program in an IPRT setting. Psychiatric Rehabilitation Skills 5:403-425, 2001
annual conference on Cognitive Remediation in Psychiatry. NY, 2006

掲載雑誌情報

出版社:株式会社医学書院

電子版ISSN:1882-126X

印刷版ISSN:0488-1281

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