文献詳細
文献概要
特集 医療・医学の課題としての身体合併症
心疾患領域との協働
著者: 和田健1
所属機関: 1広島市立病院機構広島市立広島市民病院精神科
ページ範囲:P.629 - P.637
文献購入ページに移動はじめに
急性心筋梗塞を含む冠動脈疾患やうっ血性心不全などの心疾患患者にはうつ病が合併しやすく,その予後にも影響することが近年知られるようになった17,19,23,25,34)。心疾患患者の予後やQOLを改善するために,合併したうつ病を適切に評価し,治療的介入を行っていく重要性が指摘されている14,36)。また逆にうつ病,双極性障害,統合失調症などの精神疾患患者は,心疾患に罹患しやすく,生命予後に影響するとの報告10,13,37)もみられる。したがって,精神疾患患者に合併した心疾患の管理,治療も患者の高齢化を背景に今後ますます重要な課題となることが予想される。このような臨床的課題を解決していくためには,精神科医と循環器内科医との連携・協働が必須であり,看護師や理学療法士,ソーシャルワーカーなど多職種を含めたチーム医療,集学的医療が,入院および在宅医療の場で提供されなければならない。
本稿では,心疾患とうつ病をはじめとする精神疾患との臨床的関連性について文献的考察を行い,コンサルテーション・リエゾン精神医学の視点から,リエゾン精神科医がどのように循環器内科医やその他の多職種と協働し,患者の治療およびケアにおいて機能していくべきかを述べたい。
急性心筋梗塞を含む冠動脈疾患やうっ血性心不全などの心疾患患者にはうつ病が合併しやすく,その予後にも影響することが近年知られるようになった17,19,23,25,34)。心疾患患者の予後やQOLを改善するために,合併したうつ病を適切に評価し,治療的介入を行っていく重要性が指摘されている14,36)。また逆にうつ病,双極性障害,統合失調症などの精神疾患患者は,心疾患に罹患しやすく,生命予後に影響するとの報告10,13,37)もみられる。したがって,精神疾患患者に合併した心疾患の管理,治療も患者の高齢化を背景に今後ますます重要な課題となることが予想される。このような臨床的課題を解決していくためには,精神科医と循環器内科医との連携・協働が必須であり,看護師や理学療法士,ソーシャルワーカーなど多職種を含めたチーム医療,集学的医療が,入院および在宅医療の場で提供されなければならない。
本稿では,心疾患とうつ病をはじめとする精神疾患との臨床的関連性について文献的考察を行い,コンサルテーション・リエゾン精神医学の視点から,リエゾン精神科医がどのように循環器内科医やその他の多職種と協働し,患者の治療およびケアにおいて機能していくべきかを述べたい。
参考文献
1)Archer J, Bower P, Gilbody S, et al:Collaborative care for depression and anxiety problems. Cochrane Database Syst Rev 10:CD006525, 2012
2)Berkman LF, Blumenthal J, Burg M, et al:Effects of treating depression and low perceived social support on clinical events after myocardial infarction:the Enhancing Recovery in Coronary Heart Disease Patients(ENRICHD)Randomized Trial. JAMA 289:3106-3116, 2003
3)Celano CM, Millstein RA, Bedoya CA, et al:Association between anxiety and mortality in patients with coronary artery disease:A meta-analysis. Am Heart J 170:1105-1115, 2015
4)Chong WW, Aslani P, Chen TF:Effectiveness of interventions to improve antidepressant medication adherence:a systematic review. Int J Clin Pract 65:954-975, 2011
5)Doi-Kanno M, Fukahori H:Predictors of Depression in Patients Diagnosed with Myocardial Infarction after Undergoing Percutaneous Coronary Intervention:A literature review. J Med Dent Sci 63:37-43, 2016
6)Druss BG, Bradford DW, Rosenheck RA, et al:Mental disorders and use of cardiovascular procedures after myocardial infarction. JAMA 283:506-511, 2000
7)Fan H, Yu W, Zhang Q, et al:Depression after heart failure and risk of cardiovascular and all-cause mortality:a meta-analysis. Prev Med 63:36-42, 2014
8)Gathright EC, Goldstein CM, Josephson RA, et al:Depression increases the risk of mortality in patients with heart failure:A meta-analysis. J Psychosom Res 94:82-89, 2017
9)Ghosh RK, Ball S, Prasad V, et al:Depression in heart failure:Intricate relationship, pathophysiology and most updated evidence of interventions from recent clinical studies. Int J Cardiol 224:170-177, 2016
10)Goldstein BI, Carnethon MR, Matthews KA, et al:Major Depressive Disorder and Bipolar Disorder Predispose Youth to Accelerated Atherosclerosis and Early Cardiovascular Disease:A Scientific Statement From the American Heart Association. Circulation 132:965-986, 2015
11)Hare DL, Toukhsati SR, Johansson P, et al:Depression and cardiovascular disease:a clinical review. Eur Heart J 35:1365-1372, 2014
12)Hasnain M, Vieweg WV, Lesnefsky EJ, et al:Depression screening in patients with coronary heart disease:a critical evaluation of the AHA guidelines. J Psychosom Res 71:6-12, 2011
13)Hennekens CH, Hennekens AR, Hollar D, et al:Schizophrenia and increased risks of cardiovascular disease. Am Heart J 150:1115-1121, 2005
14)Huffman JC, Adams CN, Celano CM:Collaborative Care and Related Interventions in Patients With Heart Disease:An Update and New Directions. Psychosomatics 59:1-18, 2018
15)Jeyanantham K, Kotecha D, Thanki D, et al:Effects of cognitive behavioural therapy for depression in heart failure patients:a systematic review and meta-analysis. Heart Fail Rev 22:731-741, 2017
16)Katon WJ, Lin EH, Von Korff M, et al:Collaborative care for patients with depression and chronic illnesses. N Engl J Med 363:2611-2620, 2010
17)木原康樹:非がん疾患の緩和ケア—心不全.日本医師会雑誌 146:951-953, 2017
18)Leung YW, Flora DB, Gravely S, et al:The impact of premorbid and postmorbid depression onset on mortality and cardiac morbidity among patients with coronary heart disease:meta-analysis. Psychosom Med 74:786-801, 2012
19)Lichtman JH, Bigger JT Jr., Blumenthal JA, et al:Depression and coronary heart disease:recommendations for screening, referral, and treatment:a science advisory from the American Heart Association Prevention Committee of the Council on Cardiovascular Nursing, Council on Clinical Cardiology, Council on Epidemiology and Prevention, and Interdisciplinary Council on Quality of Care and Outcomes Research:endorsed by the American Psychiatric Association. Circulation 118:1768-1775, 2008
20)Lin EH, Katon WJ, Simon GE, et al:Achieving guidelines for the treatment of depression in primary care:is physician education enough? Med Care 35:831-842, 1997
21)Mallik S, Spertus JA, Reid KJ, et al:Depressive symptoms after acute myocardial infarction:evidence for highest rates in younger women. Arch Intern Med 166:876-883, 2006
22)McEvoy JP, Meyer JM, Goff DC, et al:Prevalence of the metabolic syndrome in patients with schizophrenia:baseline results from the Clinical Antipsychotic Trials of Intervention Effectiveness(CATIE)schizophrenia trial and comparison with national estimates from NHANES III. Schizophr Res 80:19-32, 2005
23)Meijer A, Conradi HJ, Bos EH, et al:Prognostic association of depression following myocardial infarction with mortality and cardiovascular events:a meta-analysis of 25 years of research. Gen Hosp Psychiatry 33:203-216, 2011
24)National Institute for Health and Care Excellence:Depression in adults with a chronic psysical health problem:recognition and managiment. 2009 https://www.nice.org.uk/guidance/cg91
25)Nicholson A, Kuper H, Hemingway H:Depression as an aetiologic and prognostic factor in coronary heart disease:a meta-analysis of 6362 events among 146 538 participants in 54 observational studies. Eur Heart J 27:2763-2774, 2006
26)Raney LE:Integrating Primary Care and Behavioral Health:The Role of the Psychiatrist in the Collaborative Care Model. Am J Psychiatry 172:721-728, 2015
27)Rustad JK, Stern TA, Hebert KA, et al:Diagnosis and treatment of depression in patients with congestive heart failure:a review of the literature. Prim Care Companion CNS Disord 15:doi:10.4088/PCC.13r01511.Epub 2013
28)Rutledge T, Reis VA, Linke SE, et al:Depression in heart failure a meta-analytic review of prevalence, intervention effects, and associations with clinical outcomes. J Am Coll Cardiol 48:1527-1537, 2006
29)Saha S, Chant D, McGrath J:A systematic review of mortality in schizophrenia:is the differential mortality gap worsening over time? Arch Gen Psychiatry 64:1123-1131, 2007
30)Scherrer JF, Chrusciel T, Garfield LD, et al:Treatment-resistant and insufficiently treated depression and all-cause mortality following myocardial infarction. Br J Psychiatry 200:137-142, 2012
31)Sokoreli I, de Vries JJ, Pauws SC, et al:Depression and anxiety as predictors of mortality among heart failure patients:systematic review and meta-analysis. Heart Fail Rev 21:49-63, 2016
32)Spijkerman T, de Jonge P, van den Brink RH, et al:Depression following myocardial infarction:first-ever versus ongoing and recurrent episodes. Gen Hosp Psychiatry 27:411-417, 2005
33)Suzuki T, Shiga T, Kuwahara K, et al:Impact of clustered depression and anxiety on mortality and rehospitalization in patients with heart failure. J Cardiol 64:456-462, 2014
34)Thombs BD, Bass EB, Ford DE, et al:Prevalence of depression in survivors of acute myocardial infarction. J Gen Intern Med 21:30-38, 2006
35)Thombs BD, Roseman M, Coyne JC, et al:Does evidence support the American Heart Association's recommendation to screen patients for depression in cardiovascular care? An updated systematic review. PLoS One 8:e52654, 2013
36)Tully PJ, Baumeister H:Collaborative care for comorbid depression and coronary heart disease:a systematic review and meta-analysis of randomised controlled trials. BMJ Open 5:e009128, 2015
37)Van der Kooy K, van Hout H, Marwijk H, et al:Depression and the risk for cardiovascular diseases:systematic review and meta analysis. Int J Geriatr Psychiatry 22:613-626, 2007
38)Watkins LL, Koch GG, Sherwood A, et al:Association of anxiety and depression with all-cause mortality in individuals with coronary heart disease. J Am Heart Assoc 2:e000068, 2013
掲載誌情報