精神医学61巻6号

2019年06月発行

展望

抑うつと甲状腺機能

著者： 吉村淳¹

所属機関： ¹東北医科薬科大学医学部精神科学教室

ページ範囲：P.703 - P.716

文献概要

抄録　うつ病と甲状腺機能低下症との症状の類似性についてはよく指摘され，多くの医療者に周知されている。しかし，実際に双方の疾患にどの程度の関連性があり，どのような影響を及ぼし合っているかについて，国内外の論文を通しても包括的な知見はほとんど見当たらない。また，治療抵抗性うつ病に対して甲状腺ホルモン剤の付加療法があるとの認識は広まっているが，実際にどのような対象者に，どのような基準で，どのような薬剤が適応になるか，については未だ検討されていない。これらの問題に焦点を当て，抑うつと甲状腺機能の関係性について既存の報告を多角的な視点から整理して，うつ症状の治療における甲状腺機能への注視の必要性と甲状腺ホルモン剤の可能性について提唱する。

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