文献詳細
特集 精神・神経疾患に併存する過眠の背景病態と治療マネジメント
文献概要
抄録 古典的な特発性過眠症(IH)の典型例は,若年期に発症して長期間持続的に昼夜にわたる長時間睡眠と覚醒時の睡眠酩酊を呈する。IHは,治療薬となる精神刺激薬の反応性が低く高用量投与を余儀なくされることが少なくない。また,診療上重要なのは,長時間睡眠者,概日リズム睡眠障害,発達障害,気分障害の一部の症例で,IHときわめて類似した症状を呈する点である。これらを鑑別する上では,患者の症状経過,生活習慣,精神症状の評価を行うとともに,睡眠ポリグラフィ,反復睡眠潜時検査,アクチグラフィなどの検査を組み合わせて実施する必要がある。IHとこれらの周辺疾患の病態上の類似点と相違点を明らかにすることは,各疾患の理解と治療の向上につながるものと考えられる。
参考文献
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