胃と腸44巻4号

2009年04月発行

特集 早期胃癌2009 主題 2．早期胃癌の時代的変遷

早期胃癌の時代的変遷

著者： 草野央¹² 下田忠和² 谷口浩和² 片井均³ 小田一郎¹ 後藤田卓志¹

所属機関： ¹国立がんセンター中央病院内視鏡部 ²国立がんセンター臨床検査部病理 ³国立がんセンター胃外科

ページ範囲：P.465 - P.471

要旨　当院開設以来1962～2005年の切除早期胃癌について解析を行った．1990年以降早期胃癌の割合が著明に増加し，これに伴って内視鏡治療件数も増加していた．さらに，年代とともに粘膜内癌の割合の増加，平均腫瘍径の縮小を認め，わが国が取り組んできた胃癌の診断学および治療学の進歩が大きく寄与しているものと考えられた．一方，早期胃癌患者の高齢化が認められ，高齢者におけるHelicobacter pylori（HP）感染率の高さと平均余命の伸びが早期胃癌の高齢化に結びついているものと考えられた．今後はHP感染率の低下や生活環境の欧米化に伴い，胃癌の口側への移動が予測される．このことを早期胃癌の診断および治療に生かしていく必要があると考える．

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