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胃と腸45巻3号

2010年03月発行

文献概要

今月の主題 出血性小腸疾患─内視鏡診断・治療の最前線 主題

出血性小腸疾患に対する診断・治療の進め方

著者: 岡志郎1 田中信治1 宍戸孝好2 今川宏樹2 竹村嘉人2 濱田康彦2 吉田成人1 茶山一彰2

所属機関: 1広島大学内視鏡診療科 2広島大学消化器・代謝内科

ページ範囲:P.312 - P.320

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要旨 出血を来す小腸疾患は,主に血管性病変,炎症性潰瘍性病変,腫瘍性病変に分類される.現在,出血性小腸疾患を疑った場合,カプセル内視鏡検査とバルーン内視鏡検査の使い分けが重要であるが,患者背景や出血の重症度などを考慮したうえで従来のX線造影検査や血管造影検査,体外式超音波検査など他の診断法と組み合わせながら適切に検査を進めていく必要がある.大量の血便などに伴うショック状態の患者に対しては全身状態の改善が最優先であり,その後に大腸内視鏡検査に続いて小腸内視鏡検査を行うか,血管造影あるいは出血シンチグラフィを行ったうえで小腸内視鏡検査を行う.出血性小腸疾患に対する内視鏡的止血手技は,止血機序から機械的止血法,熱凝固法,薬剤局注法,薬剤撒布法に大別されるが,バルーン内視鏡の発展により従来行われていた開腹手術が回避されるなど,患者のQOL向上に貢献できるようになった.

参考文献

1)Iddan G, Meron G, Glukhovsky A, et al. Wireless capsule endoscopy. Nature 405 : 417, 2000
2)Yamamoto H, Sekine Y, Sato Y, et al. Total enteroscopy with a nonsurgical steerable double-balloon method. Gastrointest Endosc 53 : 216-220, 2001
3)Tsujikawa T, Saitoh Y, Andoh A, et al. Novel single-balloon enteroscopy for diagnosis and treatment of the small intestine : preliminary experiences. Endoscopy 40 : 11-15, 2008
4)Ohtsuka K, Kashida H, Kodama K, et al. Diagnosis and treatment of small bowel disease with a newly developed single balloon endoscope. Dig Endosc 20 : 134-137, 2008
5)眞部紀明,田中信治,福本晃,他.ダブルバルーン内視鏡を用いた小腸腫瘍性疾患の診断と治療.胃と腸 41 : 1619-1628, 2006
6)Ohmiya N, Yano T, Yamamoto H, et al. Diagnosis and treatment of obscure GI bleeding at double balloon endoscopy. Gastrointest Endosc 66 : S72-S77, 2007
7)岡志郎,田中信治,宍戸孝好,他.内視鏡による小腸の治療的アプローチ.Intestine 13 : 461-470, 2009
8)飯田三雄.小腸疾患へのアプローチ.八尾恒良,飯田三雄(編).小腸疾患の臨床.医学書院,pp3-12, 2004
9)小林広幸,渕上忠彦,堺勇二,他.消化管の出血性疾患の鑑別診断─小腸の出血性疾患.胃と腸 40 : 508-518, 2005
10)Manabe N, Tanaka S, Fukumoto A, et al. Double-balloon enteroscopy in patients with GI bleeding of obscure origin. Gastrointest Endosc 64 : 135-140, 2006
11)Jacobs MA, Mulder CJ. Double balloon endoscopy in GI hemorrhage. Gastrointest Endosc 66 : S60-62, 2007
12)大宮直木,中村正直,本田亘,他.小腸出血診断のアルゴリズム.胃と腸 43 : 410-416, 2008
13)緒方晴彦.小腸疾患の診断的アプローチ.Intestine 13 : 453-460, 2009
14)Hartmann D, Schmidt H, Bolz G, et al. A prospective two-center study comparing wireless capsule endoscopy with intraoperative enteroscopy in patients with obscure GI bleeding. Gastrointest Endosc 61 : 826-832, 2005
15)Leighton JA, Sharma VK, Hentz JG, et al. Capsule endoscopy versus push enteroscopy for evaluation of obscure gastrointestinal bleeding with 1-Year outcomes. Dig Dis Sci 51 : 891-899, 2006
16)Saperas E, Dot J, Videla S, Alvarez-Castells A, et al. Capsule endoscopy versus computed tomographic or standard angiography for the diagnosis of obscure gastrointestinal bleeding. Am J Gastroenterol 102 : 731-737, 2007
17)Filippone A, Cianci R, Milano A, et al. Obscure gastrointestinal bleeding and small bowel pathology : comparison between wireless capsule endoscopy and multidetector-row CT enteroclysis. Abdom Imaging 33 : 398-406, 2008
18)Douard R, Wind P, Berger A, et al. Role of intraoperative enteroscopy in the management of obscure gastointestinal bleeding at the time of video-capsule endoscopy. Am J Surg 198 : 6-11, 2009
19)Zhang BL, Jiang LL, Chen CX, et al. Diagnosis of obscure gastrointestinal hemorrhage with capsule endoscopy in combination with multiple-detector computed tomography. J Gastroenterol Hepatol 9, 2009
20)松井敏幸,関剛彦,八尾健史,他.炎症性小腸疾患における小腸ダブルバルーン内視鏡検査─X線検査との比較.胃と腸 40 : 1491-1502, 2005
21)Parente F, Greco S, Molteni M, et al. Imaging inflammatory bowel disease using bowel ultrasound. Eur J Gastroenterol Hepatol 17 : 283-291, 2005
22)Fukumoto A, Tanaka S, Imagawa H, et al. Usefulness and limitations of transabdominal ultrasonography for detecting small-bowel tumors. Scand J Gastroenterol 44 : 332-338, 2009
23)Raju GS, Gerson L, Das A, et al. American Gastroenterological Association(AGA)Institute medical position statement on obscure gastrointestinal bleeding. Gastroenterology 133 : 1694-1696, 2007
24)Raju GS, Gerson L, Das A, et al. American Gastroenterological Association(AGA)Institute technical review on obscure gastrointestinal bleeding. Gastroenterology 133 : 1697-1717, 2007
25)中村哲也,生沼健司,山岸秀嗣,他.Given Imaging.早期大腸癌 11 : 183-189, 2007
26)矢野智則,山本博徳.小腸出血に対するダブルバルーン内視鏡を中心とした実践的アルゴリズム.早期大腸癌 11 : 205-210, 2007
27)荒川大吾,大宮直木,中村正直,他.小腸疾患診断・治療の今後のアルゴリズム(1)出血性病変を中心に─小腸出血の診断と治療.早期大腸癌 11 : 211-215, 2007
28)河南智晴.カプセル内視鏡未導入施設におけるアルゴリズム.早期大腸癌 11 : 217-222, 2007
29)Ogata H, Kumai K, Imada, et al. Clinical impact of a newly developed capsule endoscope : usefulness of a real-time image viewer for gastric transit abnormality. J Gastroenterol 43 : 186-192, 2008
30)Niv E, Bonger I, Barkay O, et al. Effect of erythromycin on image quality and transit time of capsule endoscopy : a two-center study. World J Gastroenterol 14 : 2561-2565, 2008
31)Kameda N, Higuchi K, Shiba M, et al. A prospective, single-blind trial comparing wireless capsule endoscopy and double-balloon enteroscopy in patients with obscure gastrointestinal bleeding. J Gastroenterol 43 : 434-440, 2008
32)Li X, Chen H, Dai J, et al. Predictive role of capsule endoscopy on the insertion route of double-balloon enteroscopy. Endoscopy 41 : 762-766, 2009
33)岡志郎,田中信治.止血術─AS局注法.胃と腸 40 : 688-690, 2005
34)矢野智則,山本博徳,砂田圭二郎,他.小腸疾患・内視鏡治療の進歩.日消誌 106 : 19-25, 2009
35)Andersen K, Vogt C, Blondin D, et al. Multi-detector CT-colonography in inflammatory bowel disease : prospective analysis of CT-findings to high-resolution video colonoscopy. Eur J Radiol 58 : 140-146, 2005
36)八尾恒良,桜井俊弘,山本淳也,他.最近の腸結核─10年間の本邦報告例の解析.胃と腸 30 : 485-490, 1995
37)Matsumoto T, Kudo T, Esaki M, et al. Prevalence of non-steroidal anti-inflammatory drug-induced enteropathy determined by double-balloon endoscopy : a Japanese multicenter study. Scand J Gastroenterol 43 : 490-496, 2008
38)Niwa Y, Nakamura M, Ohmiya N, et al. Efficacy of rebamipide for diclofenac-induced small-intestinal mucosal injuries in healthy subjects : a prospective, randomized, double-blinded, placebo-controlled, cross-over study. J Gastroenterol 43 : 270-276, 2008
39)Fujimori S, Seo T, Gudis K, et al. Prevention of nonsteroidal anti-inflammatory drug-induced small-intestinal injury by prostaglandin : a pilot randomized controlled trial evaluated by capsule endoscopy. Gastrointest Endosc 69 : 1339-1346, 2009
40)松井敏幸,飯田三雄,桑野恭行,他.非特異性多発性小腸潰瘍症の長期経過.胃と腸 24 : 1157-1169, 1989
41)Spada C, Riccioni ME, Familiari P, et al. Video capsule endoscopy in small-bowel tumours : a single centre experience. Scand J Gastroenterol 43 : 497-505, 2008
42)Urbain D, De Looze D, Demedts I, et al. Video capsule endoscopy in small-bowel malignancy : a multicenter Belgian study. Endoscopy 38 : 408-411, 2008
43)Rondonotti E, Pennazio M, Toth E, et al. Small-bowel neoplasms in patients undergoing video capsule endoscopy : a multicenter European study. Endoscopy 40 : 488-495, 2008
44)Fukumoto A, Tanaka S, Shishido T, et al. Comparison of detectability of small-bowel lesions between capsule endoscopy and double-balloon endoscopy for patients with suspected small-bowel disease. Gastrointest Endosc 69 : 857-865, 2009
45)Matsumoto Y, Manabe N, Tanaka S, et al. Small-intestinal Peutz-Jeghers polyps resected by endoscopic polypectomy with double-balloon enteroscopy and removal confirmed by ultrasonography. Dig Dis Sci 51 : 2337-2340, 2006
46)岡志郎,田中信治.ダブルバルーン内視鏡(DBE)による小腸腫瘍の診断.医のあゆみ 230 : 873-878, 2009
47)蒲池紫乃,八尾恒良,大田恭弘.発生学的異常(Anomalies)─Meckel憩室. 八尾恒良,飯田三雄(編).小腸疾患の臨床.医学書院,pp95-101,2004

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1219

印刷版ISSN:0536-2180

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