胃と腸45巻5号

2010年04月発行

特集 早期大腸癌2010 ノート 5．早期大腸癌のスクリーニング

NBIによる大腸内視鏡スクリーニング

著者： 佐野寧¹ 豊田昌徳¹ 蓮池典明¹ 岩館峰雄¹ 佐野亙¹ 服部三太¹ 金川美彦¹ 一柳明弘² 生本太郎³ 小髙雅人³ 佐野馨¹

所属機関： ¹佐野病院消化器センター内科 ²佐野病院放射線科 ³佐野病院消化器センター外科

ページ範囲：P.776 - P.783

要旨　NBI（narrow band imaging）の特徴は，内視鏡の観察光の分光特性を狭帯域特性へ変更し（短波長側にシフト），病変の視認性や表面微細構造，微細血管観察の向上を可能にしたことにある．現時点でNBIが大腸内視鏡スクリーニング検査における有用性が検討されているのは以下の3項目である．（1）発見率の向上（報告がcontroversialでありさらなる検討が必要）．（2）腫瘍/非腫瘍の鑑別（optical/digital chromoendoscopyとして色素を使用せずに可能）．（3）大腸腫瘍の腺腫/癌の質的診断（深達度に関する量的診断に関しては今後の課題）．今後は微細血管（構造）分類のvalidation study，inter-intra observer variability，learning curveなどの関係を明らかにする必要があろう．

参考文献

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