胃と腸52巻7号

2017年06月発行

今月の主題 胃潰瘍は変わったか─新しい胃潰瘍学の構築を目指して

主題

小児の胃潰瘍

著者： 中山佳子¹

所属機関： ¹信州大学医学部小児医学教室

ページ範囲：P.907 - P.912

文献概要

要旨●小児の消化性潰瘍は比較的まれな疾患であり，胃潰瘍に対して十二指腸潰瘍は1.5〜10倍多いとされる．H. pylori感染症以外の胃潰瘍の原因は二次性潰瘍が多く，感染症，Zollinger-Ellison症候群などの酸分泌亢進性，好酸球性胃腸炎などのアレルギー性，NSAIDsなどの薬剤性，ストレス性などがある．急性胃粘膜病変は，頻回の嘔吐と消化管出血を伴う急性腹症として発症し，年少児においてはH. pylori初感染のことがある．小児においても上部消化管内視鏡検査は胃潰瘍の診断に有用であり，特に粘膜生検による病理組織学的な原因精査が重要である．

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