icon fsr

文献詳細

雑誌文献

胃と腸55巻12号

2020年11月発行

今月の主題 高齢者早期胃癌ESDの現状と問題点

主題

高齢者早期胃癌ESDにおける偶発症

著者: 五十嵐公洋1 平澤大1 遠藤明志1 岩屋梨絵1 齋藤宏章1 鈴木隆太1 新井田憩1 冨樫純一1 友兼正太郎1 伊藤聡司1 田中一平1 海野修平1 名和田義高1 田中由佳里1 阿部洋子1 鈴木憲次郎1 奥薗徹1 中堀昌人1 松田知己1

所属機関: 1仙台厚生病院消化器センター消化器内科

ページ範囲:P.1461 - P.1473

文献概要

要旨●本稿では,高齢者早期胃癌に対するESDの治療成績について,偶発症を中心に検討を行った.高齢者では併存疾患が多く,年齢別の偶発症の発生頻度は高い傾向を認めるが有意差はなかった.内視鏡治療自体は可能で,偶発症が生じなければ非高齢者と同程度の入院期間で対応可能である一方,ひとたび偶発症が生じると,より長期の入院を必要としていた.アスピリン,シロスタゾール以外の抗血栓薬では出血時期が遅延し,ヘモグロビン減少量が多く,特に留意が必要と思われる.

参考文献

1)Kato M, Uedo N, Hokimoto S, et al. Guidelines for gastroenterological endoscopy in patients undergoing antithrombotic treatment:2017 appendix on anticoagulants including direct oral anticoagulants. Dig Endosc 30:433-440, 2018
2)Fujimoto K, Fujishiro M, Kato M, et al. Guidelines for gastroenterological endoscopy in patients undergoing antithrombotic treatment. Dig Endosc 26:1-14, 2014
3)日本胃癌学会(編).胃癌治療ガイドライン,第5版.金原出版,2018
4)Charlson ME, Pompei P, Ales KL, et al. A new method of classifying prognostic comorbidity in longitudinal studies:development and validation. J Chronic Dis 40:373-383, 1987
5)Hatta W, Gotoda T, Oyama T, et al. A scoring system to stratify curability after endoscopic submucosal dissection for early gastric cancer:"eCura system". Am J Gastroenterol 112:874-881, 2017
6)Nishizawa T, Suzuki H, Matsuzaki J, et al. Propofol versus traditional sedative agents for endoscopic submucosal dissection. Dig Endosc 26:701-706, 2014
7)Nonaka M, Gotoda T, Kusano C, et al. Safety of gastroenterologist-guided sedation with propofol for upper gastrointestinal therapeutic endoscopy in elderly patients compared with younger patients. Gut Liver 9:38-42, 2015
8)Takimoto K, Ueda T, Shimamoto F, et al. Sedation with dexmedetomidine hydrochloride during endoscopic submucosal dissection of gastric cancer. Dig Endosc 23:176-181, 2011
9)Yoshida M, Takizawa K, Suzuki S, et al. Conventional versus traction-assisted endoscopic submucosal dissection for gastric neoplasms:a multicenter, randomized controlled trial(with video). Gastrointest Endosc 87:1231-1240, 2018
10)Tsuji K, Yoshida N, Nakanishi H, et al. Recent traction methods for endoscopic submucosal dissection. World J Gastroenterol 22:5917-5926, 2016
11)Lin JP, Zhang YP, Xue M, et al. Endoscopic submucosal dissection for early gastric cancer in elderly patients:a meta-analysis. World J Surg Oncol 13:293, 2015
12)Watari J, Tomita T, Toyoshima F, et al. The incidence of "silent" free air and aspiration pneumonia detected by CT after gastric endoscopic submucosal dissection. Gastrointest Endosc 76:1116-1123, 2012
13)Fujita I, Toyokawa T, Matsueda K, et al. Association between CT-diagnosed pneumonia and endoscopic submucosal dissection of gastric neoplasms. Digestion 94:37-43, 2016
14)Akasaka T, Nishida T, Tsutsui S, et al. Short-term outcomes of endoscopic submucosal dissection(ESD)for early gastric neoplasm:multicenter survey by Osaka university ESD study group. Dig Endosc 23:73-77, 2011
15)Park CH, Kim H, Kang YA, et al. Risk factors and prognosis of pulmonary complications after endoscopic submucosal dissection for gastric neoplasia. Dig Dis Sci 58:540-546, 2013
16)Ito S, Hotta K, Imai K, et al. Risk factors of post-endoscopic submucosal dissection electrocoagulation syndrome for colorectal neoplasm. J Gastroenterol Hepatol 33:2001-2006, 2018
17)Yamaguchi H, Fukuzawa M, Kawai T, et al. Predictive factors of postendoscopic submucosal dissection electrocoagulation syndrome and the utility of computed tomography scan after esophageal endoscopic submucosal dissection. Digestion 14:1-11, 2009
18)Murata A, Muramatsu K, Ichimiya Y, et al. Endoscopic submucosal dissection for gastric cancer in elderly Japanese patients:an observational study of financial costs of treatment based on a national administrative database. J Dig Dis 15:62-70, 2014
19)Cho SJ, Choi IJ, Kim CG, et al. Aspirin use and bleeding risk after endoscopic submucosal dissection in patients with gastric neoplasms. Endoscopy 44:114-121, 2012
20)Sanomura Y, Oka S, Tanaka S, et al. Continued use of low-dose aspirin does not increase the risk of bleeding during or after endoscopic submucosal dissection for early gastric cancer. Gastric Cancer 17:489-496, 2014
21)Igarashi K, Takizawa K, Kakushima N, et al. Should antithrombotic therapy be stopped in patients undergoing gastric endoscopic submucosal dissection? Surg Endosc 31:1746-1753, 2017
22)Oh S, Kim SG, Kim J, et al. Continuous use of thienopyridine may be as safe as low-dose aspirin in endoscopic resection of gastric tumors. Gut Liver 12:393-401, 2018
23)Ono S, Myojo M, Harada H, et al. Is it possible to perform gastric endoscopic submucosal dissection without discontinuation of a single antiplatelet of thienopyridine derivatives? Endosc Int Open 5:E943-949, 2017
24)Tounou S, Morita Y, Hosono T. Continuous aspirin use does not increase post-endoscopic dissection bleeding risk for gastric neoplasms in patients on antiplatelet therapy. Endosc Int Open 3:E31-38, 2015
25)Ono S, Fujishiro M, Yoshida N, et al. Thienopyridine derivatives as risk factors for bleeding following high risk endoscopic treatments:safe treatment on antiplatelets(STRAP)study. Endoscopy 47:632-637, 2015
26)Watanabe H, Domei T, Morimoto T, et al. Effect of 1-month dual antiplatelet therapy followed by clopidogrel vs 12-month dual antiplatelet therapy on cardiovascular and bleeding events in patients receiving PCI:the STOPDAPT-2 randomized clinical trial. JAMA 321:2414-2427, 2019
27)Mabe K, Kato M, Oba K, et al. A prospective, multicenter survey on the validity of shorter periendoscopic cessation of antithrombotic agents in Japan. J Gastroenterol 52:50-60, 2017
28)Nagata N, Yasunaga H, Matsui H, et al. Therapeutic endoscopy-related GI bleeding and thromboembolic events in patients using warfarin or direct oral anticoagulants:results from a large nationwide database analysis. Gut 67:1805-1812, 2018
29)齋藤宏章,平澤大,松田知己,他.抗凝固薬内服例における内視鏡的胃粘膜下層剝離術後出血の実態とmHAS-BLED scoreによる層別化.Gastroenterol Endosc 61(Suppl 2):2151, 2019
30)Kawata N, Ono H, Takizawa K, et al. Efficacy of polyglycolic acid sheets and fibrin glue for prevention of bleeding after gastric endoscopic submucosal dissection in patients under continued antithrombotic agents. Gastric Cancer 21:696-702, 2018
31)Goto O, Oyama T, Ono H, et al. Endoscopic hand-suturing is feasible, safe, and may reduce bleeding risk after gastric endoscopic submucosal dissection:a multicenter pilot study(with video). Gastrointest Endosc 91:1195-1202, 2020
32)Maekawa S, Nomura R, Murase T, et al. Complete closure of artificial gastric ulcer after endoscopic submucosal dissection by combined use of a single over-the-scope clip and through-the-scope clips(with videos). Surg Endosc 29:500-504, 2015

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1219

印刷版ISSN:0536-2180

雑誌購入ページに移動
icon up

本サービスは医療関係者に向けた情報提供を目的としております。
一般の方に対する情報提供を目的としたものではない事をご了承ください。
また,本サービスのご利用にあたっては,利用規約およびプライバシーポリシーへの同意が必要です。

※本サービスを使わずにご契約中の電子商品をご利用したい場合はこちら