胃と腸57巻2号

2022年02月発行

今月の主題 炎症性腸疾患の粘膜治癒を再考する 主題

潰瘍性大腸炎における粘膜治癒評価の意義—画像強調内視鏡の立場から

著者： 上村修司¹ 前田将久¹ 湯通堂和樹¹ 桑水流康介¹ 小牧蕗子¹ 田中啓仁¹ 鮫島洋一¹ 小牧祐雅¹ 佐々木文郷¹ 井戸章雄¹

所属機関： ¹鹿児島大学大学院医歯学総合研究科消化器疾患・生活習慣病学

ページ範囲：P.141 - P.148

要旨●潰瘍性大腸炎の治療目標として，内視鏡的粘膜治癒と同様に組織学的治癒の重要性が認識されるようになった．しかし，内視鏡的活動性と組織学的活動性には乖離を認めることがあり，組織学的治癒を効率的に評価できるような新たな画像認識技術が求められている．これまで内視鏡的粘膜治癒の判断には白色光観察による活動性スコアリングが用いられてきたが，近年のIEE技術の発展により，白色光観察では捉えられない微細な粘膜の炎症性所見が認識可能となった．IEE観察による内視鏡と組織学的活動性診断の相関が検証できれば，IEEは内視鏡的炎症の診断に必要不可欠な技術となると考えられる．

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