胃と腸57巻4号

2022年04月発行

今月の主題 予後不良な早期消化管癌 主題

予後不良な早期消化管癌の病理組織学的特徴—大腸癌

著者： 海崎泰治¹ 平沼知加志² 金本斐子² 鈴木勇人² 服部昌和² 道傳研司² 青柳裕之³ 波佐谷兼慶³ 原季衣¹ 小上瑛也¹

所属機関： ¹福井県立病院病理診断科 ²福井県立病院外科 ³福井県立病院消化器内科

ページ範囲：P.377 - P.386

要旨●大腸癌の予後不良である組織型および病理組織学的所見を示し，実際のT1癌症例での予後との関連性について検討した．予後不良な組織型は低分化腺癌，印環細胞癌，内分泌細胞癌，invasive micropapillary carcinoma，未分化癌が挙げられた．予後不良な病理組織学的所見は，リンパ管侵襲，静脈侵襲，神経侵襲，簇出，低分化胞巣，未熟間質，リンパ節構造のない壁外非連続性癌進展病巣が挙げられた．実際のT1大腸癌症例では，予後不良な組織型および病理組織学的所見を有する症例は非常に少数で予後に対する影響は軽微であり，病理組織学的所見による予後予測は難しいと考えられた．

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