臨床整形外科46巻12号

2011年12月発行

Lecture

腰椎椎間板ヘルニアの疼痛機序

著者： 関口美穂¹ 菊地臣一¹ 紺野愼一¹

所属機関： ¹福島県立医科大学医学部整形外科学講座

ページ範囲：P.1111 - P.1120

　腰椎椎間板ヘルニアは，代表的な腰椎変性疾患の一つである．ヘルニア塊または椎間板の膨隆による機械的圧迫因子と，炎症性サイトカインなどの化学的因子が，椎間板ヘルニアの疼痛発現の病態として着目されている．本稿では，ラット腰椎椎間板ヘルニアモデルを用いて検討した椎間板ヘルニアの疼痛発現の病態について紹介する．

参考文献

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