臨床整形外科52巻12号

2017年12月発行

誌上シンポジウム 慢性腰痛のサイエンス

—腰痛の基礎的機序—炎症性サイトカインの腰痛への関与

著者： 内田健太郎¹ 宮城正行¹ 井上玄¹ 中脇充章¹ 高野昇太郎¹ 高相晶士¹

所属機関： ¹北里大学医学部整形外科学

ページ範囲：P.1119 - P.1123

　慢性腰痛のうち，多くは病因を特定できない非特異的腰痛であると言われており，しばしば治療に難渋する．非特異的腰痛の原因として，椎間板由来，椎間関節由来，仙腸関節由来，筋膜由来，椎体由来などの要素が報告されているが，その詳細な機序は不明である．本稿では，非特異的腰痛の代表として椎間板性腰痛の病態に焦点を当て，炎症性サイトカインを介した椎間板性腰痛の基礎的発生機序について概説する．

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