臨床整形外科52巻12号

2017年12月発行

誌上シンポジウム 慢性腰痛のサイエンス

腰痛の疫学—The Wakayama Spine Studyから得られた知見

著者： 寺口真年¹ 橋爪洋² 山田宏² 吉村典子³ 吉田宗人⁴

所属機関： ¹和歌山県立医科大学附属病院紀北分院脊椎ケアセンター ²和歌山県立医科大学整形外科教室 ³東京大学22世紀医療センターロコモ予防学講座 ⁴角谷整形外科病院

ページ範囲：P.1125 - P.1131

　The Wakayama Spine Study(WSS)は大規模コホート研究ROAD(Research on Osteoarthritis Against Disability)studyのサブコホートとして，脊椎疾患の疫学データを報告してきた．本稿は腰痛の疫学として，椎間板および周囲のMRI変化と腰痛に関して述べる．腰椎にT2強調矢状断像で低信号変化した椎間板変性を1つでも有する場合は，有意に腰痛を有する結果であった(オッズ比1.57)．しかしながら椎間板変性，終板変化，そしてSchmorl結節を各画像単独で検討すると有意な関連がみられなかった．一方，画像変化がすべて組み合わさると，画像変化がない場合と比べて有意に腰痛が生じていることがわかった(オッズ比2.17)．以上から，椎間板変性および周囲の変化は組み合わせることによって腰痛との関連があることがわかった．

参考文献

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