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雑誌文献

臨床整形外科52巻9号

2017年09月発行

文献概要

誌上シンポジウム パーキンソン病と疼痛

—パーキンソン病と腰痛—脊髄刺激療法—適応と課題

著者: 牟礼英生1 平澤元浩2 永廣信治1

所属機関: 1徳島大学大学院医歯薬学研究部脳神経外科 2東京女子医科大学東医療センター脳神経外科

ページ範囲:P.861 - P.867

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 脊髄刺激療法(SCS)は,主に経皮的に脊髄硬膜外電極留置を行い,脊髄後索を刺激することにより神経障害性疼痛を抑制する神経調節治療(neuromodulation therapy)である.パーキンソン病は中脳黒質ドパミン含有神経細胞の変性に伴う不随意運動疾患とみなされてきたが,近年は自律神経障害や認知機能障害などの非運動症状に注目が集まっている.痛みもその1つであり,しばしば治療抵抗性のこともありQOLを低下させる一因となる.本稿ではSCSの概要およびパーキンソン病に対するSCSについて自験例に文献的考察を加えて解説する.

参考文献

1) Fil A, Cano-de-la-Cuerda R, Muñoz-Hellin E, et al. Pain in Parkinson disease:a review of the literature. Parkinsonism Relat Disord 2013;19:285-94;discussion 285.
2) Defazio G, Berardelli A, Fabbrini G, et al. Pain as a nonmotor symptom of Parkinson disease:evidence from a case-control study. Arch Neurol 2008;65:1191-4.
3) Broetz D, Eichner M, Gasser T, et al. Radicular and nonradicular back pain in Parkinson's disease:a controlled study. Mov Disord 2007 22:853-6.
4) Etchepare F, Rozenberg S, Mirault T, et al. Back problems in Parkinson's disease:an underestimated problem. Joint Bone Spine 2006;73:298-302.
5) Scott DJ, Heitzeg MM, Koeppe RA, et al. Variations in the human pain stress experience mediated by ventral and dorsal basal ganglia dopamine activity. J Neurosci 2006;26:10789-95.
6) Baliki MN, Geha PY, Fields HL, et al. Predicting value of pain and analgesia:nucleus accumbens response to noxious stimuli changes in the presence of chronic pain. Neuron 2010;66:149-60.
7) Djaldetti R, Shifrin A, Rogowski Z, et al. Quantitative measurement of pain sensation in patients with Parkinson disease. Neurology 2004;62:2171-5.
8) Melzack R, Wall PD. Pain mechanisms:a new theory. Science 1965;150(3699):971-9.
9) Shealy CN, Mortimer JT, Reswick JB. Electrical inhibition of pain by stimulation of the dorsal columns:preliminary clinical report. Anesth Analg 1967;46:489-91.
10) Agari T, Date I. [Spinal cord stimulation revisited]. No Shinkei Geka 2013;41:851-74.
11) El-Khoury C, Hawwa N, Baliki M, et al. Attenuation of neuropathic pain by segmental and supraspinal activation of the dorsal column system in awake rats. Neuroscience 2002;112:541-53.
12) Baron R, Binder A, Wasner G. Neuropathic pain:diagnosis, pathophysiological mechanisms, and treatment. Lancet Neurol 2010;9:807-19.
13) Cui JG, Linderoth B, Meyerson BA. Effects of spinal cord stimulation on touch-evoked allodynia involve GABAergic mechanisms. An experimental study in the mononeuropathic rat. Pain 1996;66:287-95.
14) Society TBP. Spinal cord stimulation for the management of pain:recommendations for best clinical practice. 2009;Available from:https://www.britishpainsociety.org/static/uploads/resources/files/book_scs_main_1.pdf.
15) Ford B. Pain in Parkinson's disease. Clin Neurosci 1998;5:63-72.
16) Yoshii F. [Pain and sensory disturbance in Parkinson disease]. Brain Nerve 2012;64:364-72.
17) de Andrade EM, Ghilardi MG, Cury RG, et al. Spinal cord stimulation for Parkinson's disease:a systematic review. Neurosurg Rev 2016;39:27-35;discussion 35.
18) Thevathasan W, Mazzone P, Jha A, et al. Spinal cord stimulation failed to relieve akinesia or restore locomotion in Parkinson disease. Neurology 2010;74:1325-7.
19) Fénelon G, Goujon C, Gurruchaga JM, et al. Spinal cord stimulation for chronic pain improved motor function in a patient with Parkinson's disease. Parkinsonism Relat Disord 2012;18:213-4.
20) Agari T, Date I. Spinal cord stimulation for the treatment of abnormal posture and gait disorder in patients with Parkinson's disease. Neurol Med Chir (Tokyo) 2012;52:470-4.
21) Landi A, Trezza A, Pirillo D, et al. Spinal cord stimulation for the treatment of sensory symptoms in advanced Parkinson's disease. Neuromodulation 2013;16:276-9.
22) Hassan S, Amer S, Alwaki A, et al. A patient with Parkinson's disease benefits from spinal cord stimulation. J Clin Neurosci 2013;20:1155-6.
23) Nishioka K, Nakajima M. Beneficial therapeutic effects of spinal cord stimulation in advanced cases of Parkinson's disease with intractable chronic pain:a case series. Neuromodulation 2015;18:751-3.
24) 牟礼英生,平澤元浩,永廣信治.当科で経験した難治性疼痛に対する脊髄刺激療法の検討.特にパーキンソン病に伴う腰下肢痛に関して.脊髄外科 2014;28:287-9.
25) Soltani F, Lalkhen A.Improvement of parkinsonian symptomos with spinal cord stimulation:consequence or coincidence. J Neurol Neurosurg Psychiatry 2013;84(11):e2.
26) Babat LB, McLain RF, Bingaman W, et al. Spinal surgery in patients with Parkinson's disease:construct failure and progressive deformity. Spine (Phila Pa 1976) 2004;29:2006-12.
27) Sarkiss CA, Fogg GA, Skovril B, et al. To operate or not?:A literature review of surgical outcomes in 95 patients with Parkinson's disease undergoing spine surgery. Clin Neurol Neurosurg 2015;134:122-5.
28) Fuentes R, Petersson P, Siesser WB, et al. Spinal cord stimulation restores locomotion in animal models of Parkinson's disease. Science 2009;323:1578-82.

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1286

印刷版ISSN:0557-0433

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