臨床整形外科55巻4号

2020年04月発行

特集 人工関節周囲感染の現状と展望　国際コンセンサスを踏まえて

人工関節感染の病理組織学的診断

著者： 稲垣有佐¹² 宗本充¹² 内原好信¹² 田中康仁¹

所属機関： ¹奈良県立医科大学整形外科学教室 ²

ページ範囲：P.335 - P.338

　人工関節周囲感染(periprosthetic joint infection：PJI)の診断において，新規診断法が実用化される今日においても，病理組織学的診断は重要な位置を占め，Proposed 2018 International Consensus Meeting Criteria for PJIにおいても診断項目となっている．一般的なパラフィン固定の永久標本に加え，人工関節周囲感染が疑われる症例から採取された標本は，凍結標本として処理され，術中迅速診断に活用される．主に多形核白血球の浸潤を評価する病理組織学的診断の精度は，検体を採取する部位，検体数，処理法，検者などに依存している．Chloroacetate esterase染色は多形核白血球の視認性を向上させる方法である．

参考文献

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