臨床整形外科56巻11号

2021年11月発行

特集 末梢神経の再建2021

同種処理神経の現状と展望

著者： 赤羽美香¹ 伊藤聰一郎²

所属機関： ¹金沢市立病院整形外科 ²帝京大学戦略的イノベーション研究センター材料強度科学部門

ページ範囲：P.1349 - P.1353

　自家神経移植術の代替法として，同種処理神経が開発され欧米で臨床応用されるようになった．しかし，同種処理神経は脱細胞化処理によりSchwann細胞や神経栄養因子などの液性因子が失われるため，長い神経欠損や大径神経への移植では術後成績が低下することが報告されている．この欠点を補う方法として，神経の脱細胞化処理後に支持細胞や栄養因子を補充する方法が試みられている．本稿では，同種処理神経移植の臨床成績と，それを向上するために行われている近年の研究を紹介する．

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