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耳鼻咽喉科・頭頸部外科86巻1号

2014年01月発行

特集 耳鼻咽喉科・頭頸部外科領域の最新トピックス

≪頭頸部腫瘍領域≫

HPVウイルス関連中咽頭癌

著者: 安井俊道1 猪原秀典1

所属機関: 1大阪大学大学院医学系研究科脳神経感覚器外科学講座耳鼻咽喉科・頭頸部外科学

ページ範囲:P.82 - P.86

文献概要

POINT

●HPV関連中咽頭癌が増加している。

●HPV関連中咽頭癌の臨床像とは。

●HPV関連中咽頭癌は非関連癌に比べて予後がよい。

●HPV関連中咽頭癌には,陰窩から発生する微小癌が存在する。

●囊胞性リンパ節とHPVの関係性とは。

●HPV関連中咽頭癌の今後の展望。

参考文献

1)Chaturvedi AK, et al:Human papillomavirus and rising oropharyngeal cancer incidence in the United States. J Clin Oncol 29:4294-4301, 2011
2)Hammarstedt L, et al:Human papillomavirus as a risk factor for the increase in incidence of tonsillar cancer. Int J Cancer 119:2620-2623, 2006
3)Rampias T, et al:E6 and e7 gene silencing and transformed phenotype of human papillomavirus 16-positive oropharyngeal cancer cells. J Natl Cancer Inst 101:412-423, 2009
4)Gillison ML, et al:Evidence for a causal association between human papillomavirus and a subset of head and neck cancers. J Natl Cancer Inst 92:709-720, 2000
5)D'Souza G, et al:Case-control study of human papillomavirus and oropharyngeal cancer. N Engl J Med 356:1944-1956, 2007
6)Gillison ML, et al:Human papillomavirus and diseases of the upper airway:head and neck cancer and respiratory papillomatosis. Vaccine 30(Suppl 5):F34-54, 2012
7)D'Souza G, et al:The role of HPV in head and neck cancer and review of the HPV vaccine. Prev Med 53(Suppl 1):S5-S11, 2011
8)Robinson M, et al:Refining the diagnosis of oropharyngeal squamous cell carcinoma using human papillomavirus testing. Oral Oncol 46:492-496, 2010
9)Singhi AD, et al:Comparison of human papillomavirus in situ hybridization and p16 immunohistochemistry in the detection of human papillomavirus-associated head and neck cancer based on a prospective clinical experience. Cancer 116:2166-2173, 2010
10)El-Naggar AK, et al:p16 expression as a surrogate marker for HPV-related oropharyngeal carcinoma:a guide for interpretative relevance and consistency. Head Neck 34:459-461, 2012
11)Hong A, et al:HPV Status of Oropharyngeal Cancer by Combination HPV DNA/p16 Testing:Biological Relevance of Discordant Results. Ann Surg Oncol Epub 04 December, 2012
12)Lewis JS Jr:p16 Immunohistochemistry as a standalone test for risk stratification in oropharyngeal squamous cell carcinoma. Head Neck Pathol 6(Suppl 1):S75-82, 2012
13)Ang KK, et al:Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med 363:24-35, 2010
14)Ragin CC, et al:Survival of squamous cell carcinoma of the head and neck in relation to human papillomavirus infection:review and meta-analysis. Int J Cancer 121:1813-1820, 2007
15)O'Rorke MA, et al:Human papillomavirus related head and neck cancer survival:a systematic review and meta-analysis. Oral Oncol 48:1191-1201, 2012
16)Fakhry C, et al:Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial. J Natl Cancer Inst 100:261-269, 2008
17)Worden FP, et al:Chemoselection as a strategy for organ preservation in advanced oropharynx cancer:response and survival positively associated with HPV16 copy number. J Clin Oncol 26:3138-3146, 2008
18)Lassen P, et al:Effect of HPV-associated p16INK4A expression on response to radiotherapy and survival in squamous cell carcinoma of the head and neck. J Clin Oncol 27:1992-1998, 2009
19)Rischin D, et al:Prognostic significance of p16INK4A and human papillomavirus in patients with oropharyngeal cancer treated on TROG 02.02 phase Ⅲ trial. J Clin Oncol 28:4142-4148, 2010
20)Posner MR, et al:Survival and human papillomavirus in oropharynx cancer in TAX 324:a subset analysis from an international phase Ⅲ trial. Ann Oncol 22:1071-1077, 2011
21)Cianchetti M, et al:Diagnostic evaluation of squamous cell carcinoma metastatic to cervical lymph nodes from an unknown head and neck primary site. Laryngoscope 119:2348-2354, 2009
22)Waltonen JD, et al:Tonsillectomy vs. deep tonsil biopsies in detecting occult tonsil tumors. Laryngoscope 119:102-106, 2009
23)Kothari P, et al:Role of tonsillectomy in the search for a squamous cell carcinoma from an unknown primary in the head and neck. Br J Oral Maxillofac Surg 46:283-287, 2008
24)Goldenberg D, et al:Cystic lymph node metastasis in patients with head and neck cancer:An HPV-associated phenomenon. Head Neck 30:898-903, 2008

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1316

印刷版ISSN:0914-3491

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