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耳鼻咽喉科・頭頸部外科86巻10号

2014年09月発行

文献概要

特集 咽頭癌・頸部食道癌の治療戦略Update ≪個別化治療の現在≫

PETからみた咽頭癌の個別化治療

著者: 花本敦1

所属機関: 1大阪大学大学院医学系研究科耳鼻咽喉科・頭頸部外科学

ページ範囲:P.812 - P.818

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POINT

●ワールブルグ効果によって咽頭癌の糖の取り込みは亢進する。

●FDG-PETは普及し3次元解析も一般化。

●MTV,TLGが化学放射線療法の予後を予測する能力が高い。

●治療効果判定としてのPERCISTの評価。

●MTVやPERCISTを用いての個別化治療。

参考文献

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2)Boellaard R, et al:Effects of noise, image resolution, and ROI definition on the accuracy of standard uptake values:a simulation study. J Nucl Med 45:1519-1527, 2004
3)Kamel EM, et al:Recurrent laryngeal nerve palsy in patients with lung cancer:detection with PET-CT image fusion--report of six cases. Radiology 224:153-156, 2002
4)Salesiotis AN, et al:Molecular markers predictive of response and prognosis in the patient with advanced squamous cell carcinoma of the head and neck:evolution of a model beyond TNM staging. Curr Opin Oncol 12:229-239, 2000
5)Inohara H, et al:Impact of FDG-PET on prediction of clinical outcome after concurrent chemoradiotherapy in hypopharyngeal carcinoma. Mol Imaging Biol 12:89-97, 2010
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8)Schwartz DL, et al:FDG-PET prediction of head and neck squamous cell cancer outcomes. Arch Otolaryngol Head Neck Surg 130:1361-1367, 2004
9)Roh JL, et al:2-[18F]-Fluoro-2-deoxy-D-glucose positron emission tomography as guidance for primary treatment in patients with advanced-stage resectable squamous cell carcinoma of the larynx and hypopharynx. Eur J Surg Onco 33:790-795, 2007
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F]-fluorodeoxyglucose positron emission tomography/computed tomography predicts short-term outcome to radiotherapy with or without chemotherapy in pharyngeal cancer. Clin Cancer Res 15:5861-5868, 2009
13)Hanamoto A, et al:Volumetric PET/CT parameters predict local response of head and neck squamous cell carcinomas to chemoradiotherapy. Cancer Med 2014(in press)
14)Abgral R, et al:Does 18F-FDG PET/CT improve the detection of posttreatment recurrence of head and neck squamous cell carcinoma in patients negative for disease on clinical follow-up? J Nucl Med 50:24-29, 2009
15)Wahl RL, et al:From RECIST to PERCIST:Evolving Considerations for PET response criteria in solid tumors. J Nucl Med 50:122S-150S, 2009
F-FDG PET in managing the neck in node-positive head and neck cancer after chemoradiotherapy. Acta Otolaryngol 129:893-899, 2009
17)Porceddu SV, et al:Utility of positron emission tomography for the detection of disease in residual neck nodes after(chemo)radiotherapy in head and neck cancer. Head Neck 27:175-181, 2005
18)Yanagawa M, et al:Evaluation of response to neoadjuvant chemotherapy for esophageal cancer:PET response criteria in solid tumors versus response evaluation criteria in solid tumors. J Nucl Med 53:872-880, 2012

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1316

印刷版ISSN:0914-3491

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