耳鼻咽喉科・頭頸部外科87巻10号

2015年09月発行

特集 長引く咳を診る

咳に対する対症療法

著者： 西耕一¹

所属機関： ¹石川県立中央病院呼吸器内科

ページ範囲：P.782 - P.789

POINT

●咳嗽治療薬には原因疾患に特異的な治療薬と非特異的な治療薬（いわゆる鎮咳薬）がある。

●長引く咳嗽の場合はできるだけ原因疾患を明らかにし，特異的治療を行う。

●特異的治療を行っても効果が不十分な咳嗽や原因不明の咳嗽により患者のQOLが著しく低下している場合に，非特異的治療薬を投与する。

●乾性咳嗽の非特異的治療薬として主に中枢性鎮咳薬が用いられるが，鎮咳効果は限定的である。

●湿性咳嗽の非特異的治療薬として主に去痰薬が用いられるが，鎮咳効果は限定的である。

●新規の強力な非特異的咳嗽治療薬の開発が待たれている。

参考文献

1）日本呼吸器学会咳嗽に関するガイドライン第2版作成委員会：咳嗽の分類と原因疾患．咳嗽に関するガイドライン第2版，日本呼吸器学会咳嗽に関するガイドライン第2版作成委員会（編）．東京，2012，pp7-8

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