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雑誌文献

耳鼻咽喉科・頭頸部外科91巻2号

2019年02月発行

文献概要

特集 ここまできた! 頭頸部希少癌の治療戦略

腺様囊胞癌—集学的治療のup-to-date

著者: 別府慎太郎1 門脇重憲2 花井信広1

所属機関: 1愛知県がんセンター中央病院頭頸部外科部 2愛知県がんセンター中央病院薬物療法部

ページ範囲:P.144 - P.149

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POINT

●潜在リンパ節転移に対する治療の意義は不明瞭であり,前向きの臨床試験が待たれる。

●近年,粒子線治療が手術に次ぐ局所治療法として期待されている。

●遠隔転移症例は予後不良である一方で,肺転移単独例など緩徐進行性の場合もある。稀な腫瘍であることから全身化学療法の生存延長効果については十分なエビデンスがなく,治療目標は症状緩和になる。

参考文献

1)日本頭頸部癌学会(編):頭頸部癌診療ガイドライン 2018年版.金原出版,東京,2017,pp70-73,133-138
2)NCCN Clinical Practice Guidelines in Oncology, head and neck cancers(Ver.1, 2018) https://www.nccn.org/professionals/physician_gls/pdf/head-and-neck_blocks.pdf
3)Amit M, et al:Elective neck dissection in patients with head and neck adenoid cystic carcinoma:an international collaborative study. Ann Surg Oncol 22:1353-1359, 2015
4)Wenig BM:Atlas of head and neck pathology 2nd ed. Elsevier, Philadelphia, 2008, pp631-637
5)Min R, et al:Salivay gland adenoid cystic carcinoma with cervical lymph node metastasis:a preliminary study of 62 cases. Int J Oral Maxillofac Surg 41:952-957, 2012
6)Amit M, et al:Incidence of cervical lymph node metastasis and its association with outcomes in patients with adenoid cystic carcinoma. An international collaborative study. Head Neck 37:1032-1037, 2015
7)Balamucki CJ, et al:Adenoid cystic carcinoma of the head and neck. Am J Otolaryngol 33:510-518, 2012
8)Lee SY, et al:Characteristics, management of the neck, and oncological outcomes of malignant minor salivary gland tumours in the oral and sinonasal regions. Br J Oral Maxillofac Surg 51:e142-147, 2013
9)Sulaiman NS, et al:Multicenter study of carbon-ion radiotherapy for adenoid cystic carcinoma of the head and neck:Sub-analysis of the Japan Carbon-Ion Radiation Oncology Study Group(J-CROS)Study(1402 HN). Int J Radiat Oncol Biol Phys 100:639-646, 2018
10)Takagi M, et al:Treatment outcomes of practicle radiotherapy using protons or carbon ions as a single-modality therapy for adenoid cystic carcinoma of the head and neck. Radiother Oncol 113:364-370, 2014
11)Spiro RH:Distant metastasis in adenoid cystic carcinoma of salivary origin. Am J Surg 174:495-498, 1997
12)Van der Wal JE, et al:Distant metastases of adenoid cystic carcinoma of the salivary glands and the value of diagnostic examinations during follow-up. Head Neck 24:779-783, 2002
13)Locati LD, et al:Treatment relevant target immunophenotyping of 139 salivary gland carcinomas(SGCs). Oral Oncol 45:986-990, 2009
14)Zhang J, et al:Expressions of nuclear factor kappaB, inducible nitric oxide synthase, and vascular endothelial growth factor in adenoid cystic carcinoma of salivary glands:correlations with the angiogenesis and clinical outcome. Clin Cancer Res 11:7334-7343, 2005
15)Even C, et al:Notch pathway inhibition with LY3039478 in adenoid cystic carcinoma(ACC). J Clin Oncol 35(suppl):abstr 6024, 2017
16)Zhu G, et al:Phase Ⅱ trial of apatinib in patients with recurrent and/or metastatic adenoid cystic carcinoma of the head and neck:Updated analysis. J Clin Oncol 36(suppl):abstr 6026, 2018
17)Tchekmedyian V, et al:A phase Ⅱ study of lenvatinib in patients with progressive, recurrent/metastatic adenoid cystic carcinoma. J Clin Oncol 36(suppl):abstr 6022, 2018
18)Cohen RB, et al:Pembrolizumab for the treatment of advanced salivary gland carcinoma:findings of the phase 1b KEYNOTE-028 study. Am J Clin Oncol, 2018[Epub ahead of print]

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1316

印刷版ISSN:0914-3491

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