耳鼻咽喉科・頭頸部外科94巻5号

2022年04月発行

増刊号 結果の読み方がよくわかる！　耳鼻咽喉科検査ガイド Ⅵ．頭頸部腫瘍の検査

免疫染色

著者： 村瀬貴幸¹ 稲垣宏¹

所属機関： ¹名古屋市立大学大学院医学研究科臨床病態病理学

ページ範囲：P.204 - P.212

POINT

◆2017年のWHO分類により，顎口腔領域，鼻咽頭領域，唾液腺における腫瘍組織型が整理されたが，各組織型の鑑別には免疫染色や遺伝子解析が重要視されている．

◆唾液腺腫瘍では組織型に特異的な遺伝子異常が明らかにされ，遺伝子解析が病理診断において必要となっているが，大学を除いた市中総合病院では検査体制の確立は難しい状況である．

◆唾液腺腫瘍では組織型に特異性の高い免疫染色用の抗体も開発されつつあり，市中総合病院の病理検査室においても検索可能になっていくものと考えられる．

参考文献

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