耳鼻咽喉科・頭頸部外科95巻4号

2023年04月発行

特集 睡眠時無呼吸症候群の診療エッセンシャル

《総論》

睡眠時無呼吸症候群が社会に与える影響

著者： 和田裕雄¹ 谷川武¹

所属機関： ¹順天堂大学大学院医学研究科公衆衛生学

ページ範囲：P.299 - P.304

文献概要

POINT

●睡眠時無呼吸症候群およびその併存症はabsenteeismあるいはpresenteeismの原因となり，また，医療コストの増加要因となる。

●睡眠時無呼吸症候群そのものの症状は個人レベルのパフォーマンスの低下と関連する。

●睡眠時無呼吸症候群があると社会経済状況が悪化し，また，低い社会経済状況は睡眠時無呼吸症候群の発症と関連するため，両者が悪循環を形成し，社会格差の原因となっている。

●睡眠時無呼吸症候群の予防および医療は，社会格差解消の一助となっている可能性がある。

参考文献

1）和田裕雄・他：睡眠呼吸障害と運転リスク．日医師会誌149：272，2020

2）Van Dongen HP, et al：The cumulative cost of additional wakefulness：dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation. Sleep 26：117-126, 2003

3）Chin K, et al：Response shift in perception of sleepiness in obstructive sleep apnea-hypopnea syndrome before and after treatment with nasal CPAP. Sleep 27：490-493, 2004

4）Nakano H, et al：Validation of a single-channel airflow monitor for screening of sleep-disordered breathing. Eur Respir J 32：1060-1067, 2008

5）Wada H, et al：Harmonizing work with the treatment and prevention of sleep disordered breathing in commercial motor vehicle drivers：implications for health and productivity management. Ind Health 57：3-9, 2019

6）Hirsch Allen AJM, et al：The effect of OSA on work disability and work-related injuries. Chest 147：1422-1428, 2015

7）Guglielmi O, et al：Occupational health of patients with obstructive sleep apnea syndrome：a systematic review. Sleep Breath 19：35-44, 2015

8）Jennum P, et al：Socioeconomic and humanistic burden of illness of excessive daytime sleepiness severity associated with obstructive sleep apnoea in the European Union 5. Sleep Med 84：46-55, 2021

9）Benton ML, et al：Treatment of obstructive sleep apnea syndrome with nasal positive airway pressure improves golf performance. J Clin Sleep Med 9：1237-1242, 2013

10）Wada H, et al：Impact of sleep disordered breathing on performance in judo players. BMJ Open Sport Exerc Med 5：e000418, 2019

11）Burks SV, et al：Nonadherence with employer-mandated sleep apnea treatment and increased risk of serious truck crashes. Sleep 39：967-975, 2016

12）Akashiba T, et al：Sleep apnea syndrome（SAS）clinical practice guidelines 2020. Respir Investig 60：3-32, 2022

13）和田裕雄・他：職域における睡眠呼吸障害と健康経営．産業衛誌61：89-94，2019

14）Etindele Sosso FA, et al：Socioeconomic disparities in obstructive sleep apnea：a systematic review of empirical research. Sleep Breath 25：1729-1739, 2021

15）Guglielmi O, et al：Association between socioeconomic status, belonging to an ethnic minority and obstructive sleep apnea：a systematic review of the literature. Sleep Med 57：100-106, 2019

16）Palm A, et al：Socioeconomic factors and adherence to CPAP：the population-based course of disease in patients reported to the Swedish CPAP oxygen and ventilator registry study. Chest 160：1481-1491, 2021

17）Wickwire EM, et al：Lower socioeconomic status and co-morbid conditions are associated with reduced continuous positive airway pressure adherence among older adult medicare beneficiaries with obstructive sleep apnea. Sleep 43：zsaa122, 2020

18）Silva GE, et al：Association between obstructive sleep apnea and multiple involuntary job loss history among recently unemployed adults. Sleep Health 7：118-122, 2021

19）Gozal D：Sleep-disordered breathing and school performance in children. Pediatrics 102：616-620, 1998

20）Marcus CL, et al；Childhood Adenotonsillectomy Trial（CHAT）：A randomized trial of adenotonsillectomy for childhood sleep apnea. N Engl J Med 368：2366-2376, 2013

21）Sakamoto N, et al：Sleep duration, snoring prevalence, obesity, and behavioral problems in a large cohort of primary school students in Japan. Sleep 40：zsw082, 2017

22）Wada H, et al：Pectus excavatum is associated with sleep-related breathing disorders in children. Eur Respir J 54：1900524, 2019

23）Wada H, et al：Nocturnal enuresis and sleep disordered breathing in primary school children：potential implications. Pediatr Pulmonol 53：1541-1548, 2018

24）Park JW, et al：Socioeconomic inequalities in pediatric obstructive sleep apnea. J Clin Sleep Med 18：637-645, 2022

25）Borsoi L, et al：The invisible costs of obstructive sleep apnea（OSA）：systematic review and cost-of-illness analysis. PLoS One 17：e0268677, 2022