耳鼻咽喉科・頭頸部外科96巻4号

2024年04月発行

特集 頭頸部がん診療のControversy 化学放射線療法 どっちを選ぶ？ Triweekly CDDP-CRT vs Weekly CDDP-CRT

Weekly CDDP-CRT

著者： 浜田誠二郎¹ 加納里志¹

所属機関： ¹北海道大学大学院医学研究院耳鼻咽喉科・頭頸部外科学教室

ページ範囲：P.330 - P.333

Point

●術後化学放射線療法（CRT）においては，JCOG1008試験にて，weekly CDDP-CRT（シスプラチン40mg/m²）がtriweekly CDDP-CRT（100mg/m²）に対して非劣性であることが証明された。

●初回治療においても，weekly CDDP-CRTがtriweekly CDDP-CRTと比較して非劣性であると報告されている。

●高齢者に関しては，有害事象によりtriweekly CDDP-CRTの実施・完遂が困難である可能性があり，weekly CDDP-CRTでの検証が望まれる。

参考文献

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