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理学療法ジャーナル49巻1号

2015年01月発行

文献概要

特集 姿勢と歩行—理学療法士の診るべきこと 生理的変化か異常か適応か? 各病態における姿勢と歩行の解釈

2.パーキンソン病患者における姿勢と歩行

著者: 堀場充哉1

所属機関: 1名古屋市立大学病院リハビリテーション部

ページ範囲:P.29 - P.37

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パーキンソン病の姿勢異常と歩行障害

 歩行障害はほとんどすべてのパーキンソン病に出現し,移動能力の低下や死亡率増加の原因となる.パーキンソン病の歩行障害は,歩幅や歩隔の減少,歩行速度の低下,歩行中の腕振り減少や消失といった運動症状だけでなく,すくみ足,加速歩行に代表されるような,精神症状,認知症状などの非運動症状あるいは環境にも影響を受ける症状としての側面も有する1)

 また,パーキンソン病の歩行障害の特徴は疾病の進行によっても変化する.発症早期から中期では,歩幅の減少や歩行速度の低下が特徴であるが,はっきりしない場合も多い.年齢や気分障害(抑うつ)などの他の要因やサブタイプによっても歩行障害の程度,特徴は影響される.一方,進行期以降になると,歩行障害はより複雑になり,すくみ足や加速歩行,姿勢不安定性が出現し,転倒に至る患者も著しく増加する.この病期になると,いわゆるパーキンソン姿勢と呼ばれる前傾前屈姿勢(stooped posture)に加え,頸部前屈やcamptocormia,Pisa徴候など頸部や体幹の姿勢異常を呈する場合もある.本稿では,パーキンソン病の姿勢異常や歩行障害について概説するとともに,理学療法やその効果に関する知見を紹介する.

参考文献

1)Ebersbach G, et al:Clinical syndromes:Parkinsonian gait. Mov Disord 28:1552-1559, 2013
2)Mallet N, et al:Cortical inputs and GABA interneurons imbalance projection neurons in the striatum of parkinsonian rats. J Neurosci 26:3875-3884, 2006
3)Takakusaki K, et al:Role of basal ganglia-brainstem pathways in the control of motor behaviors. Neurosci Res 50:137-151, 2004
4)Takakusaki K, et al:Basal ganglia efferents to the brainstem centers controlling postural muscle tone and locomotion:a new concept for understanding motor disorders in basal ganglia dysfunction. Neuroscience 119:293-308, 2003
5)Karachi C, et al:Cholinergic mesencephalic neurons are involved in gait and postural disorders in Parkinson disease. J Clin Invest 120:2745-2754, 2010
6)Ovadia A, et al:Increased susceptibility to MPTP toxicity in middle-aged rhesus monkeys. Neurobiol Aging 16:931-937, 1995
7)Braak H, et al:Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol Aging 24:197-211, 2003
8)Ashour R, et al:Joint and skeletal deformities in Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy. Mov Disord 21:1856-1863, 2006
9)Dietz V, et al:Balance control in Parkinson's disease. Gait Posture 1:77-84, 1993
10)Jacobs JV, et al:Can stooped posture explain multidirectional postural instability in patients with Parkinson's disease? Exp Brain Res 166:78-88, 2005
11)Bloem BR, et al:Are automatic postural responses in patients with Parkinson's disease abnormal due to their stooped posture? Exp Brain Res 124:481-488, 1999
12)Doherty KM, et al:Postural deformities in Parkinson's disease. Lancet Neurol 10:538-549, 2011
13)Djaldetti R, et al:Camptocormia(bent spine)in patients with Parkinson's disease—characterization and possible pathogenesis of an unusual phenomenon. Mov Disord 14:443-447, 1999
14)Azher SN, et al:Camptocormia:pathogenesis, classification, and response to therapy. Neurology 65:355-359, 2005
15)Tiple D, et al:Camptocormia in Parkinson disease:an epidemiological and clinical study. J Neurol Neurosurg Psychiatry 80:145-148, 2009
16)Abe K, et al:Camptocormia in Parkinson's disease. Parkinsons Dis 2010;doi:10.4061/2010/267640
17)Lepoutre AC, et al:A specific clinical pattern of camptocormia in Parkinson's disease. J Neurol Neurosurg Psychiatry 77:1229-1234, 2006
18)Wunderlich S, et al:Camptocormia in Parkinson's disease mimicked by focal myositis of the paraspinal muscles. Mov Disord 17:598-600, 2002
19)Furusawa Y, et al:Role of the external oblique muscle in upper camptocormia for patients with Parkinson's disease. Mov Disord 27:802-803, 2012
20)von Coelln R, et al:Ultrasound-guided injection of the iliopsoas muscle with botulinum toxin in camptocormia. Mov Disord 23:889-892, 2008
21)Gerton BK, et al:Backpack treatment for camptocormia. Mov Disord 25:247-248, 2010
22)Kashihara K, et al:Dropped head syndrome in Parkinson's disease. Mov Disord 21:1213-1216, 2006
23)van de Warrenburg BP, et al:The phenomenon of disproportionate antecollis in Parkinson's disease and multiple system atrophy. Mov Disord 22:2325-2331, 2007
24)Papapetropoulos S, et al:Retrocollis:classification, clinical phenotype, treatment outcomes and risk factors. Eur Neurol 59:71-75, 2008
25)Tassorelli C, et al:Pisa syndrome in Parkinson's disease:clinical, electromyographic, and radiological characterization. Mov Disord 27:227-235, 2012
26)Vitale C, et al:Vestibular impairment and adaptive postural imbalance in parkinsonian patients with lateral trunk flexion. Mov Disord 26:1458-1463, 2011
27)Santamato A, et al:Botulinum toxin type A and a rehabilitation program in the treatment of Pisa syndrome in Parkinson's disease. J Neurol 257:139-141, 2010
28)Baik JS, et al:Scoliosis in patients with Parkinson's disease. J Clin Neurol 5:91-94, 2009
29)Di Matteo A, et al:Lateral trunk flexion in Parkinson's disease:EMG features disclose two different underlying pathophysiological mechanisms. J Neurol 258:740-745, 2010
30)Laroche M, et al:Bent spine syndrome(camptocormia):a retrospective study of 63 patients. Joint Bone Spine 77:593-596, 2010
31)Nieuwboer A, et al:Abnormalities of the spatiotemporal characteristics of gait at the onset of freezing in Parkinson's disease. Mov Disord 16:1066-1075, 2001
32)Hausdorff JM:Gait dynamics, fractals and falls:finding meaning in the stride-to-stride fluctuations of human walking. Hum Mov Sci 26:555-589, 2007
33)Albani G, et al:“Masters and servants”in parkinsonian gait:a three-dimensional analysis of biomechanical changes sensitive to disease progression. Funct Neurol 29:99-105, 2014
34)瀬尾和弥,他:パーキンソン病患者の歩行障害に対する3次元動作解析の試み.総合リハ39:57-62,2011
35)Huang Y, et al:The effects of stride length and stride frequency on trunk coordination in human walking. Gait Posture 31:444-449, 2010
36)Alice N, et al:Does freezing in Parkinson's disease change limb coordination?A kinematic analysis. J Neurol 254:1268-1277, 2007
37)Halliday SE, et al:The initiation of gait in young, elderly, and Parkinson's disease subjects. Gait Posture 8:8-14, 1998
38)Delval A, et al:Why we should study gait initiation in Parkinson's disease. Neurophysiol Clin 44:69-76, 2014
39)Amboni M, et al:Freezing of gait and executive functions in patients with Parkinson's disease. Mov Disord 23:395-400, 2008
40)Wu T, et al:Neural correlates of dual task performance in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry 79:760-766, 2008
41)Jones D, et al:Everyday walking with Parkinson's disease:understanding personal challenges and strategies. Disabil Rehabil 30:1213-1221, 2008
42)Plotnik M, et al:Effects of cognitive function on gait and dual tasking abilities in patients with Parkinson's disease suffering from motor response fluctuations. Exp Brain Res 208:169-179, 2011
43)Kehagia AA, et al:Neuropsychological and clinical heterogeneity of cognitive impairment and dementia in patients with Parkinson's disease. Lancet Neurol 9:1200-1213, 2010
44)Kelly VE, et al:A review of dual-task walking deficits in people with Parkinson's disease:motor and cognitive contributions, mechanisms, and clinical implications. Parkinsons Dis 2012. doi:10.1155/2012/918719
45)Cohen RG, et al:Freezing of gait is associated with a mismatch between motor imagery and motor execution in narrow doorways, not with failure to judge doorway passability. Neuropsychologia 49:3981-3988, 2011
46)Royal Dutch Society for Physiotherapy:KNGF guideline for physical therapy in patients with Parkinson's disease. Supplement to the Dutch Journal of Physiotherapy 114, 2004
47)Morris ME:Movement disorders in people with Parkinson disease:a model for physical therapy. Phys Ther 80:578-597, 2000
48)林 康子,他:パーキンソン病の姿勢障害に対する理学療法—特に首下がりについて.MB Med Rehabil 135:45-53,2011
49)Capecci M, et al:Postural rehabilitation and Kinesio taping for axial postural disorders in Parkinson's disease. Arch Phys Med Rehabil 95:1067-1075, 2014
50)武澤信夫,他:Unified Parkinson's disease rating scaleと三次元動作解析を用いたパーキンソン病患者のリハビリテーションの有効性の検討.Jpn J Rehabil Med 47:791-800,2010
51)Morris M, et al:Three-dimensional gait biomechanics in Parkinson's disease:evidence for a centrally mediated amplitude regulation disorder. Mov Disord 20:40-50, 2005

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1359

印刷版ISSN:0915-0552

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