BRAIN and NERVE－神経研究の進歩63巻1号

2011年01月発行

総説

認知と運動の統合過程を支える神経基盤

著者： 星英司¹ 中山義久¹ 山形朋子¹ 佐賀洋介¹ 橋本雅史¹ 有村奈利子¹ 丹治順¹

所属機関： ¹玉川大学脳科学研究所

ページ範囲：P.59 - P.68

文献概要

はじめに

　ヒトで発達した高次脳機能の主要特徴の1つは，多様な情報を関連づける能力である。認知情報と運動情報を統合する過程は，こうした情報処理を必要とするので，これを支える神経メカニズムを解析することは，ヒト脳の機能的基盤を理解するにあたって重要な洞察を与える。本稿では，前頭葉外側面を中心としたネットワークを構成する領野が認知と運動の統合過程において果たすさまざまな役割を具体的に解説したうえで，仮想的レベルならびに物理的動作レベルの情報表現という観点からさまざまな知見を統一的に説明することを試みる。こうした新しい視点は，健常時の脳機能に深い理解をもたらすだけでなく，失行，麻痺，不随意運動，運動失調などの病態メカニズムを説明するための基盤を提供し，基礎研究と臨床応用の重要な接点となることが期待される。

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