BRAIN and NERVE－神経研究の進歩64巻8号

2012年08月発行

特集 線条体の基礎と臨床

大脳皮質-線条体の神経回路

著者： 高田昌彦¹

所属機関： ¹京都大学霊長類研究所分子生理研究部門統合脳システム分野

ページ範囲：P.871 - P.879

文献概要

はじめに

　われわれは行動するとき，達成すべき行動目標を正しく設定するため，視覚，聴覚，体性感覚など，外界からの感覚情報や，学習，記憶，情動など，自己が持つ内部情報に基づいて行動計画を立案し，実行する。行動の発現と制御には，これらの情報やこれらの情報から生成される認知情報を扱う大脳皮質と，大脳皮質のほぼ全域から入力を受ける大脳基底核が重要な役割を担っている。線条体は大脳基底核の入力核であり，運動，感覚，認知，情動など，大脳皮質に由来するさまざまなタイプの情報が入力する。

　本稿では，このような皮質線条体入力をはじめ，大脳皮質と線条体をつなぐ神経ネットワークについて概説する。

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