BRAIN and NERVE－神経研究の進歩66巻1号

2014年01月発行

特集 日常生活の脳科学

空腹による脳機能制御

著者： 平野恭敬¹ 齊藤実²

所属機関： ¹京都大学大学院医学研究科メディカルイノベーションセンターSKプロジェクト ²東京都医学総合研究所運動・感覚システム分野学習記憶プロジェクト

ページ範囲：P.41 - P.48

文献概要

生物は栄養摂取状態と内的な代謝環境を調節させるため，動物におけるホルモン作用などでみられるようにさまざまな生体応答を備えている。本稿では，異なる生物種での絶食応容を概観し，動物においてどのように絶食が脳機能を変化させるかを紹介する。さらに筆者らのショウジョウバエを用いた最近の発見により，絶食時には記憶機能も変化することが明らかになったので，併せて紹介する。われわれがどのように自己を制御しているのか，その包括的理解の一助になることを期待する。

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