文献詳細
特集 神経筋疾患の超音波診断
文献概要
神経筋疾患の診断に,超音波検査が一般的に利用されるようになりつつある。筋萎縮性側索硬化症(ALS)の診断においても,超音波検査の応用が始まっている。ALS診断で試用されている超音波の検査項目には,エコー輝度,筋の厚さ,線維束性収縮がある。現時点では手技の標準化,一般化はまだ十分とはいえない。しかし,ALSで特徴的である線維束性収縮は非侵襲的かつ容易な手技で明確に描出でき,診断に貢献できる可能性がある。ALSでは確定診断に至るまで,筋電図検査が繰り返し行われることが多い。今後,痛みのないALS診断への超音波検査の貢献が期待される。
参考文献
1) Lambert EH: Electromyography in amyotrophic lateral sclerosis. Norris FH, Kurland LT (eds): Motor Neuron Diseases: Research on amyotrophic lateral sclerosis and related disorders. Grune & Statton, New York, 1969, pp135-153
2) Brooks BR: El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. Subcommittee on Motor Neuron Diseases/Amyotrophic Lateral Sclerosis of the World Federation of Neurology Research Group on Neuromuscular Diseases and the El Escorial "Clinical limits of amyotrophic lateral sclerosis" workshop contributors. J Neurol Sci 124(Suppl): 96-107, 1994
3) Brooks BR, Miller RG, Swash M, Munsat TL; World Federation of Neurology Research Group on Motor Neuron Diseases: El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 1: 293-299, 2000
4) de Carvalho M, Dengler R, Eisen A, England JD, Kaji R, et al: Electrodiagnostic criteria for diagnosis of ALS. Clin Neurophysiol 119: 497-503, 2008
5) Higashihara M, Sonoo M, Imafuku I, Fukutake T, Kamakura K, et al: Fasciculation potentials in amyotrophic lateral sclerosis and the diagnostic yield of the Awaji algorithm. Muscle Nerve 45: 175-182, 2012
6) de Carvalho M: Does Awaji decrease diagnostic yield in ALS? Muscle Nerve 46: 142-143, 2012
7) Falck B, Alaranta H: Fibrillation potentials, positive sharp waves and fasciculation in the intrinsic muscles of the foot in healthy subjects. J Neurol Neurosurg Psychiatry 46: 681-683, 1983
8) Roth G, Magistris MR: Neuropathies with prolonged conduction block, single and grouped fasciculations, localized limb myokymia. Electroencephalogr Clin Neurophysiol 67: 428-438, 1987
9) Dumitru D, Diaz CA, King JC: Prevalence of denervation in paraspinal and foot intrinsic musculature. Am J Phys Med Rehabil 80: 482-490, 2001
currents in human neuropathy and motor neuron disease estimated by latent addition. Clin Neurophysiol 117: 2451-2458, 2006
11) Kanai K, Kuwabara S, Misawa S, Tamura N, Ogawara K, et al: Altered axonal excitability properties in amyotrophic lateral sclerosis: impaired potassium channel function related to disease stage. Brain 129: 953-962, 2006
12) Sonoo M, Kuwabara S, Shimizu T, Komori T, Hirashima F, et al; Tokyo Metropolitan Neuromuscular Electrodiagnosis Study Group: Utility of trapezius EMG for diagnosis of amyotrophic lateral sclerosis. Muscle Nerve 39: 63-70, 2009
13) Cartwright MS, Walker FO, Griffin LP, Caress JB: Peripheral nerve and muscle ultrasound in amyotrophic lateral sclerosis. Muscle Nerve 44: 346-351, 2011
14) Arts IM, van Rooij FG, Overeem S, Pillen S, Janssen HM, et al: Quantitative muscle ultrasonography in amyotrophic lateral sclerosis. Ultrasound Med Biol 34: 354-361, 2008
15) Arts IM, Pillen S, Schelhaas HJ, Overeem S, Zwarts MJ: Normal values for quantitative muscle ultrasonography in adults. Muscle Nerve 41: 32-41, 2010
16) Wohlfart G: Collateral regeneration from residual motor nerve fibers in amyotrophic lateral sclerosis. Neurology 7: 124-134, 1957
17) Pillen S, Tak RO, Zwarts MJ, Lammens MM, Verrijp KN, et al: Skeletal muscle ultrasound: correlation between fibrous tissue and echo intensity. Ultrasound Med Biol 35: 443-6, 2009
18) Arts IM, Overeem S, Pillen S, Kleine BU, Boekestein WA, et al: Muscle ultrasonography: a diagnostic tool for amyotrophic lateral sclerosis. Clin Neurophysiol 123: 1662-7, 2012
19) Noto YI, Shiga K, Tsuji Y, Kondo M, Tokuda T,et al: Contrasting echogenicity in FDP-FCU: a diagnostic ultrasound pattern in sporadic inclusion body myositis. Muscle Nerve, 2013 Aug 27 [Epub ahead of print]
20) Misawa S, Noto Y, Shibuya K, Isose S, Sekiguchi Y, et al: Ultrasonographic detection of fasciculations markedly increases diagnostic sensitivity of ALS. Neurology 77: 1532-1537, 2011
21) Lee CD, Song Y, Peltier AC, Jarquin-Valdivia AA, Donofrio PD: Muscle ultrasound quantifies the rate of reduction of muscle thickness in amyotrophic lateral sclerosis. Muscle Nerve 42: 814-819, 2010
22) Arts IM, Overeem S, Pillen S, Schelhaas HJ, Zwarts MJ: Muscle ultrasonography to predict survival in amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry 82: 552-554, 2011
23) Yoshioka Y, Ohwada A, Sekiya M, Takahashi F, Ueki J, et al: Ultrasonographic evaluation of the diaphragm in patients with amyotrophic lateral sclerosis. Respirology 12: 304-307, 2007
24) Hiwatani Y, Sakata M, Miwa H: Ultrasonography of the diaphragm in amyotrophic lateral sclerosis: clinical significance in assessment of respiratory functions. Amyotroph Lateral Scler Frontotemporal Degener 14: 127-131, 2013
25) Pillen S, Nienhuis M, van Dijk JP, Arts IM, van Alfen N, et al: Muscles alive: ultrasound detects fibrillations. Clin Neurophysiol 120: 932-936, 2009
26) van Alfen N, Nienhuis M, Zwarts MJ, Pillen S: Detection of fibrillations using muscle ultrasound: diagnostic accuracy and identification of pitfalls. Muscle Nerve 43: 178-182, 2011
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