BRAIN and NERVE－神経研究の進歩67巻1号

2015年01月発行

原著

パーキンソン病における認知機能障害と姿勢保持障害との関連

著者： 大湾喜行¹ 村上秀友¹ 森友紀子¹ 山岸慶子¹ 渡辺大士¹ 加藤大貴¹ 毛束真知子¹ 河村満¹

所属機関： ¹昭和大学医学部内科学講座神経内科学部門

ページ範囲：P.99 - P.104

文献概要

パーキンソン病患者65例にNeurobehavioral Cognitive Status ExaminationとUnified Parkinson's Disease Rating Scaleを実施し，認知機能障害と運動症状との関連性を検討した。前者のうち遂行機能と視空間認知機能をともに評価する下位検査の構成が姿勢保持障害と最も強い相関を示した。前頭葉のほか頭頂葉もパーキンソン病の姿勢保持機能に関与している可能性がある。

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