BRAIN and NERVE－神経研究の進歩68巻2号

2016年02月発行

特集 筋疾患の認知機能障害

筋強直性ジストロフィー1型の社会的認知障害

著者： 小早川睦貴¹

所属機関： ¹東京情報大学総合情報学部総合情報学科

ページ範囲：P.137 - P.144

文献概要

筋強直性ジストロフィー1型（DM 1）では自閉症スペクトラムに類似した行動を示すことが報告されており，これは社会的認知機能の低下として捉えることができる。表情認知の検討では，怒りや嫌悪などネガティブな表情に対する感度の低下がみられ，また心の理論については，言語・非言語の両面から機能低下が示されている。こうした異常は島皮質，側頭葉前方部，前頭葉底部の白質の異常と関連があるものと推察される。

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