BRAIN and NERVE－神経研究の進歩68巻4号

2016年04月発行

増大特集 治せる認知症

ビタミンB₁₂・葉酸欠乏と認知症

著者： 吉澤利弘¹

所属機関： ¹NTT東日本関東病院神経内科

ページ範囲：P.407 - P.420

文献概要

「治せる認知症」の原因としてビタミン欠乏は頻度は稀ながら重要な課題である。とりわけ高齢者の認知症診療ではビタミンB₁₂欠乏が原因と考えられる症例に遭遇する頻度が高い。一方，葉酸はビタミンB₁₂と代謝経路上密接な関係を有し，その欠乏とビタミンB₁₂欠乏の間には共通点も多い。したがって本論では，ビタミンB₁₂欠乏と葉酸欠乏に焦点を絞り，これらの欠乏による認知症を診療するうえで必要な情報を概説する。

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