BRAIN and NERVE－神経研究の進歩68巻7号

2016年07月発行

増大特集 認知症の危険因子と防御因子

性格と認知症

著者： 増井幸恵¹

所属機関： ¹東京都健康長寿医療センター研究所福祉と生活ケア研究チーム

ページ範囲：P.793 - P.798

文献概要

性格と認知症の関係に関する先行研究では，両者の関係を3つの視点から検討している：①性格が認知症発症のリスク要因であるという視点，②認知症発症に先だって性格の変化があるという視点，③特定の性格傾向が認知症発症後のBPSD（behavioral and psychological symptoms of dementia）の内容を規定するという視点，である。本論文では，性格および性格特性についての解説を行った後，この3つの視点からの研究をそれぞれ概観する。

参考文献

1)Ryff CD, Kwan CML, Singer BH: Personality and aging: flourishing agendas and future challenges. Birren JE, Schaie KW (eds): Handbook of the Psychology of Aging 5th ed. Academic Press, San Diego, 2001, pp477-499

2)Costa PT Jr, McCrae RR: Revised Neo Personality Inventory (NEO-PI-R) and NEO Five-Factor Inventory (NEO-FFI) Professional Manual. Psychological Assessment Resources, Florida, 1992

3)Roberts BW, DelVecchio WF: The rank-order consistency of personality traits from childhood to old age: a quantitative review of longitudinal studies. Psychol Bull 126: 3-25, 2000

4)Terracciano A, McCrae RR, Brant LJ, Costa PT Jr: Hierarchical linear modeling analyses of the NEO-PI-R scales in the Baltimore Longitudinal Study of Aging. Psychol Aging 20: 493-506, 2005

5)Terracciano A, Costa PT Jr: Smoking and the Five-Factor Model of personality. Addiction 99: 472-481, 2004

6)Hakulinen C, Hintsanen M, Munafò MR, Virtanen M, Kivimäki M, et al: Personality and smoking: individual-participant meta-analysis of nine cohort studies. Addiction 110: 1844-1852, 2015

7)Bogg T, Roberts BW: Conscientiousness and health-related behaviors: a meta-analysis of the leading behavioral contributors to mortality. Psychol Bull 130: 887-919, 2004

8)Steunenberg B, Beekman AT, Deeg DJ, Kerkhof AJ: Personality and the onset of depression in late life. J Affect Disord 92: 243-251, 2006

9)Marshall GN, Wortman CB, Vickers RR Jr, Kusulas JW, Hervig LK: The five-factor model of personality as a framework for personality-health research. J Pers Soc Psychol 67: 278-286, 1994

10)Swickert RJ, Rosentreter CJ, Hittner JB, Mushrush JE: Extraversion, social support processes, and stress. Pers Individ Dif 32: 877-891, 2002

11)Friedman HS, Tucker JS, Tomlinson-Keasey C, Schwartz JE, Wingard DL, et al: Does childhood personality predict longevity? J Pers Soc Psychol 65: 176-185, 1993

12)Wilson RS, Mendes de Leon CF, Bienias JL, Evans DA, Bennett DA: Personality and mortality in old age. J Gerontol B Psychol Sci Soc Sci 59: P110-P116, 2004

13)Wilson RS, Krueger KR, Gu L, Bienias JL, Mendes de Leon CF, et al: Neuroticism, extraversion, and mortality in a defined population of older persons. Psychosom Med 67: 841-845, 2005

14)Iwasa H, Masui Y, Gondo Y, Inagaki H, Kawaai C, et al: Personality and all-cause mortality among older adults dwelling in a Japanese community: a five-year population-based prospective cohort study. Am J Geriatr Psychiatry 16: 399-405, 2008

15)Low LF, Harrison F, Lackersteen SM: Does personality affect risk for dementia? A systematic review and meta-analysis. Am J Geriatr Psychiatry 21: 713-728. 2013

16)Hayward RD, Taylor WD, Smoski MJ, Steffens DC, Payne ME: Association of five-factor model personality domains and facets with presence, onset, and treatment outcomes of major depression in older adults. Am J Geriatr Psychiatry 21: 88-96, 2013

17)Kendler KS, Neale MC, Sullivan P, Corey LA, Gardner CO, et al: A population-based twin study in women of smoking initiation and nicotine dependence. Psychol Med 29: 299-308, 1999

18)Heath AC, Bucholz KK, Madden PA, Dinwiddie SH, Slutske WS, et al: Genetic and environmental contributions to alcohol dependence risk in a national twin sample: consistency of findings in women and men. Psychol Med 27: 1381-1396, 1997

19)Duberstein PR, Chapman BP, Tindle HA, Sink KM, Bamonti P, et al: Personality and risk for Alzheimer's disease in adults 72 years of age and older: a 6-year follow-up. Psychol Aging 26: 351-362, 2011

20)Wang HX, Karp A, Herlitz A, Crowe M, Kåreholt I, et al: Personality and lifestyle in relation to dementia incidence. Neurology 72: 253-259, 2009

21)Wilson RS, Schneider JA, Arnold SE, Bienias JL, Bennett DA: Conscientiousness and the incidence of Alzheimer disease and mild cognitive impairment. Arch Gen Psychiatry 64: 1204-1212, 2007

22)Glosser G, Clark C, Freundlich B, Kliner-Krenzel L, Flaherty P, et al: A controlled investigation of current and premorbid personality: characteristics of Parkinson's disease patients. Mov Disord 10: 201-206, 1995

23)Dawson DV, Welsh-Bohmer KA, Siegler IC: Premorbid personality predicts level of rated personality change in patients with Alzheimer disease. Alzheimer Dis Assoc Disord 14: 11-19, 2000

24)Rankin KP, Kramer JH, Mychack P, Miller BL: Double dissociation of social functioning in frontotemporal dementia. Neurology 60: 266-271, 2003

25)Torrente F, Pose M, Gleichgerrcht E, Torralva T, López P, et al: Personality changes in dementia: are they disease specific and universal? Alzheimer Dis Assoc Disord 28: 261-268, 2014

26)Smith-Gamble V, Baiyewu O, Perkins AJ, Gureje O, Hall KS, et al: Informant reports of changes in personality predict dementia in a population-based study of elderly african americans and yoruba. Am J Geriatr Psychiatry 10: 724-732, 2002

27)Balsis S, Carpenter BD, Storandt M: Personality change precedes clinical diagnosis of dementia of the Alzheimer type. J Gerontol B Psychol Sci Soc Sci 60: P98-P101, 2005

28)Yoneda T, Rush J, Berg AI, Johansson B, Piccinin AM: Trajectories of personality traits preceding dementia diagnosis. J Gerontol B Psychol Sci Soc Sci, 2016 Mar 4［Epub ahead of print］

29)Prior J, Abraham R, Nicholas H, Chan T, Vanvlymen J, et al: Are premorbid abnormal personality traits associated with behavioural and psychological symptoms in dementia? Int J Geriatr Psychiatry, 2016 Mar 10［Epub ahead of print］

30)Zielin S, McCabe M: Exploring the relationship between premorbid personality and dementia-related behaviors. J Gerontol Nurs 42: 40-48, 2016

31)高橋　智: 認知症のBPSD. 日本老年医学会雑誌48: 195-204, 2011