BRAIN and NERVE－神経研究の進歩69巻1号

2017年01月発行

特集 近年注目されている白質脳症

臨床概念としてのgliomatosis cerebri

著者： 杉山一彦¹

所属機関： ¹広島大学病院がん化学療法科

ページ範囲：P.35 - P.43

文献概要

Gliomatosis cerebriは3葉以上の白質に浸潤像を持つ特殊な神経膠腫の一亜型である。現在ではMRIを中心とする画像診断で病変の広がりを確認し，手術材料の病理診断で神経膠腫細胞を確認すればよい。広範な病変の広がりに比べて臨床症状は軽微であり，臨床概念として重要であるが，形態学的診断と分子病理学的診断とは乖離があり，新しいWHO脳腫瘍病理分類のentityからは削除された。

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