BRAIN and NERVE－神経研究の進歩69巻7号

2017年07月発行

増大特集 あしたのアルツハイマー病治療

アルツハイマー病のバイオインフォマティクス解析

著者： 菊地正隆¹ 中谷明弘¹

所属機関： ¹大阪大学大学院医学系研究科ゲノム情報学共同研究講座

ページ範囲：P.835 - P.842

文献概要

マイクロアレイや次世代シークエンサーの普及に伴い，大規模な生体情報であるオミックスデータが取得可能となった。これによりアルツハイマー病の複雑な病態が明らかになりつつある。オミックスデータからの情報抽出にバイオインフォマティクスを駆使した解析が必須である。本稿ではオミックスデータの中でもゲノミクスとトランスクリプトミクスを中心に，われわれが行ってきた研究を交え，これまで報告されてきたアルツハイマー病研究について概説する。

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