BRAIN and NERVE－神経研究の進歩70巻11号

2018年11月発行

増大特集 脳科学で解き明かす精神神経症候

感覚間相互作用の障害—パーキンソン病の新しい認知機能障害

著者： 本間元康¹

所属機関： ¹杏林大学医学部生理学教室

ページ範囲：P.1157 - P.1163

文献概要

対象の認知に関連する感覚は多くの場合単一ではなく複数にまたがっており，さらに感覚間で相互作用が起きている。一方で，パーキンソン病は嗅覚の障害を含めさまざまな認知機能障害を引き起こすことが示されているが，近年の研究において，パーキンソン病は視覚と嗅覚の感覚間相互作用にも障害をきたすことが報告された。本論では，感覚間相互作用の処理モデルとパーキンソン病の病態機序を踏まえながら，感覚間相互作用の障害を考察する。さらにその障害が病気の前兆指標として使用できる可能性を議論する。

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