BRAIN and NERVE－神経研究の進歩70巻11号

2018年11月発行

増大特集 脳科学で解き明かす精神神経症候

筋痛性脳脊髄炎／慢性疲労症候群の脳科学研究

著者： 渡辺恭良¹²³⁴

所属機関： ¹特定国立研究開発法人理化学研究所生命機能科学研究センター ²特定国立研究開発法人理化学研究所健康生き活き羅針盤リサーチコンプレックス推進プログラム ³公立大学法人大阪市立大学健康科学イノベーションセンター ⁴一般社団法人日本疲労学会

ページ範囲：P.1193 - P.1201

文献概要

筋痛性脳脊髄炎/慢性疲労症候群（ME/CFS）は，原因不明の激しい疲労・倦怠感とともに，労作後に増悪する極度の倦怠感，微熱，疼痛，脱力，認知機能障害，睡眠障害などの多彩な症状が長期にわたり継続し，日常生活や社会生活に支障をきたす疾患である。私たちは，この疾患に対し，血液因子や機能検査による客観的な疾患バイオマーカーを探索するとともに，PETやMRI，MEGなどを用いたイメージング研究により，ME/CFSの脳科学を推進してきた。

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