BRAIN and NERVE－神経研究の進歩70巻12号

2018年12月発行

総説

大脳皮質の単位回路 オープンアクセス

著者： 細谷俊彦¹ 中川直¹² 米田泰輔¹³ 丸岡久人¹

所属機関： ¹国立研究開発法人理化学研究所脳神経科学研究センター局所神経回路研究チーム ²鹿児島大学大学院医歯学総合研究科神経筋生理学分野 ³自然科学研究機構生理学研究所視覚情報処理研究部門

ページ範囲：P.1381 - P.1388

文献概要

大脳皮質に単位回路が繰り返した構造があるかは不明だった。われわれはさまざまな皮質領野において第Ⅴ層の神経細胞が細胞タイプ特異的なクラスター（マイクロカラム）を形成し六方格子状に並ぶことを見出した。マイクロカラムの細胞は共通な神経入力を持ち，類似した神経活動を示した。これらは第Ⅴ層がマイクロカラムを単位とした繰返し構造を持つことを示し，多数のマイクロカラムによる並列処理が多様な皮質機能を担うことを示唆する。

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