BRAIN and NERVE－神経研究の進歩70巻7号

2018年07月発行

増大特集 記憶と忘却に関わる脳のしくみ—分子機構から健忘の症候まで

側頭葉性健忘

著者： 菊池大一¹ 藤井俊勝²

所属機関： ¹東北医科薬科大学医学部老年神経内科学 ²東北福祉大学健康科学部

ページ範囲：P.783 - P.794

文献概要

内側側頭葉が記憶において重要な神経構造であることは，症例H.M.により明らかになった。両側内側側頭葉切除術により重度の健忘を呈したH.M.の神経心理学的な研究は，陳述記憶と非陳述記憶，短期記憶と長期記憶，というヒト記憶の分類につながった。内側側頭葉は特に記憶の固定化の過程において重要な役割を果たすが，その過程の心理学的および神経学的な機序は，逆向性健忘やてんかん性健忘の研究から検討することができる。

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