BRAIN and NERVE－神経研究の進歩71巻2号

2019年02月発行

総説

統合失調症における視床と社会機能の関連性

著者： 越山太輔¹ 笠井清登¹²

所属機関： ¹東京大学大学院医学系研究科精神医学分野 ²東京大学国際高等研究所ニューロインテリジェンス国際研究機構

ページ範囲：P.155 - P.160

文献概要

統合失調症を持つ方々は社会認知能力の障害により日常の社会生活に多くの困難を抱えている。しかしその神経基盤の解明は十分に進んでいない。筆者らは統合失調症の社会機能障害の神経基盤について，大脳皮質下構造である視床に着目して神経回路異常の同定につとめ，視床と前頭葉との神経ネットワーク異常が社会機能障害に関連する可能性を示した。これらの知見は，統合失調症の新たな治療法の開発に貢献すると考えられる。

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