BRAIN and NERVE－神経研究の進歩72巻11号

2020年11月発行

総説

短時間持続性片側神経痛様頭痛発作（SUNHA）の臨床

著者： 菊井祥二¹ 團野大介¹ 竹島多賀夫¹

所属機関： ¹富永病院脳神経内科・頭痛センター

ページ範囲：P.1295 - P.1306

文献概要

短時間持続性片側神経痛様頭痛発作（SUNHA）は短時間で重度の頭痛発作と同側の自律神経症状を特徴とする。SUNHAには結膜充血と流涙の両方を有するSUNCTとどちらか一方を有するSUNAが含まれる。難治性であるが，リドカイン持続静注とラモトリギンが最も効果的である。薬剤抵抗例では，三叉神経に対する微小血管減圧やニューロモジュレーションが試みられている。SUNCT，SUNAと三叉神経痛には臨床的，治療的，放射線学的に重複があり，国際頭痛分類第3版では別疾患であるが，同じ障害の連続体を構成する可能性も議論されている。

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