ログイン
ランキング
お知らせ
ログイン
文献詳細
特集 超高齢期の精神神経疾患を診る
文献概要
超高齢期の脊椎疾患として，姿勢異常の主因となる脊柱変形を取り上げた。胸腰椎の後弯変形を中心とした脊柱変形はADLおよびQOLを障害し，外科的矯正手術も行われるようになっている。高齢パーキンソン病患者も骨粗鬆症と易転倒性から脊椎圧迫骨折を合併し，姿勢異常を悪化させる。そのほか，高齢者で増加しているびまん性特発性骨増殖症と非骨傷性頸髄損傷についても論じた。超高齢者診療では脊椎をはじめ運動器疾患の素養も求められる。
参考文献
1)Yakovlev PI: Paraplegia in flexion of cerebral origin. J Neuropathol Exp Neurol 13: 267-296, 1954 (in Adams RD, Victor M: Principles of Neurology, 5th ed. McGraw-Hill, New York, 1993, p106)
2)Kado DM, Prenovost K, Crandall C: Narrative review: hyperkyphosis in older persons. Ann Intern Med 147: 330-338, 2007
3)Glassman SD, Bridwell K, Dimar JR, Horton W, Berven S, et al: The impact of positive sagittal balance in adult spinal deformity. Spine (Phila Pa 1976) 30: 2024-2029, 2005
4)Diebo BG, Shah NV, Boachie-Adjei O, Zhu F, Rothenfluh DA, et al: Adult spinal deformity. Lancet 394: 160-172, 2019
5)Itoi E: Roentgenographic analysis of posture in spinal osteoporotics. Spine (Phila Pa 1976) 16: 750-756, 1991
6)坂野友啓: 脊柱アライメントの評価法—画像診断から. 脊椎脊髄30: 259-263, 2017
7)Boulay C, Tardieu C, Hecquet J, Benaim C, Mouilleseaux B, et al: Sagittal alignment of spine and pelvis regulated by pelvic incidence: standard values and prediction of lordosis. Eur Spine J 15: 415-422, 2006
8)Schwab F, Unger B, Blondel B, Buchowski J, Coe J, et al: Scoliosis Research Society-Schwab adult spinal deformity classification: a validation study. Spine (Phila Pa 1976) 37: 1077-1082, 2012
9)小林徹也, 熱田裕司, 松野丈夫: 腰椎変性後弯症の病態と自然経過. 脊椎脊髄22: 687-693, 2009
10)宮腰尚久: 加齢に伴う姿勢の変化と脊柱後弯症. 脊椎脊髄22: 448-452, 2009
11)海渡貴司: 首下がり症候群の手術治療—胸椎・腰椎手術で治る首下がりとは？ 脊椎脊髄31: 1061-1065, 2018
12)大江 慎, 戸川大輔, 長谷川智彦, 大和 雄, 小林 祥, 他: 日本人における胸腰椎・骨盤矢状面アライメントの男女別正常値（一部頸椎を含む）と自然経過. 脊椎脊髄30: 271-276, 2017
13)紺野愼一: 腰椎背筋群の運動時コンパートメント症候群. 脊椎脊髄23: 691-695, 2010
14)八木 満, 藤田順之, 石井 賢, 中村雅也, 松本守雄, 他: 脊柱矢状面バランスと筋萎縮. 脊椎脊髄30: 579-584, 2017
15)長総義弘, 菊池臣一, 紺野愼一: 腰痛症性間欠跛行の臨床的検討. 整・災外35: 683-688, 1992
16)Imagama S, Ito Z, Wakao N, Seki T, Hirano K, et al: Influence of spinal sagittal alignment, body balance, muscle strength, and physical ability on falling of middle-aged and elderly males. Eur Spine J 22: 1346-1353, 2013
17)Kasukawa Y, Miyakoshi N, Hongo M, Ishikawa Y, Noguchi H, et al: Relationships between falls, spinal curvature, spinal mobility and back extensor strength in elderly people. J Bone Miner Metab 28: 82-87, 2010
18)Polomsky M, Siddall KA, Salvador R, Dubecz A, Donahue LA, et al: Association of kyphosis and spinal skeletal abnormalities with intrathoracic stomach: a link toward understanding its pathogenesis. J Am Coll Surg 208: 562-569, 2009
19)Harrison RA, Siminoski K, Vethanayagam D, Majumdar SR: Osteoporosis-related kyphosis and impairments in pulmonary function: a systematic review. J Bone Miner Res 22: 447-457, 2007
20)Culham EG, Jimenez HA, King CE: Thoracic kyphosis, rib mobility, and lung volumes in normal women and women with osteoporosis. Spine (Phila Pa 1976) 19: 1250-1255, 1994
21)本郷道生, 宮腰尚久, 島田洋一: 高齢者脊柱変形に対する保存療法—胸腰椎部・骨盤: 運動療法. 脊椎脊髄30: 339-344, 2017
22)Mika A, Unnithan VB, Mika P: Difference in thoracic kyphosis and in back muscle strength in women with bone loss due to osteoporosis. Spine (Phila Pa 1976) 30: 241-246, 2005
23)Bansal S, Katzman WB, Giangregorio LM: Exercise for improving age-related hyperkyphotic posture: a systematic review. Arch Phys Med Rehabil 95: 129-140, 2014
24)Srivanitchapoom P, Hallet M: Camptocormia in Parkinson's disease: definition, epidemiology, pathogenesis and treatment modalities. J Neurol Neurosurg Psychiatry 87: 75-85, 2016
25)Watanabe K, Hirano T, Katsumi K, Ohashi M, Shoji H, et al: Characteristics of spinopelvic alignment in Parkinson's disease: comparison with adult spinal deformity. J Orthop Sci 22: 16-21, 2017
26)山田孝子, 加知輝彦, 安藤一也: パーキンソン病における骨粗鬆症と骨折. 日老医誌32: 637-640, 1995
27)Ishizaki F, Harada T, Katayama S, Abe H, Nakamura S: Relationship between osteopenia and clinical characteristics of Parkinson's disease. Mov Disord 8: 507-511, 1993
28)Torsney KM, Noyce AJ, Doherty KM, Bestwick JP, Dobson R, et al: Bone health in Parkinson's disease: a systematic review and meta-analysis. J Neurol Neurosurg Psychiatry 85: 1159-1166, 2014
29)Dennison EM, Compston JE, Flahive J, Siris ES, Gehlbach SH, et al: Effect of co-morbidities on fracture risk: findings from the global longitudinal study of osteoporosis in women (GLOW). Bone 50: 1288-1293, 2012
30)Pickering RM, Grimbergen YAM, Rigney U, Ashburn A, Mazibrada G, et al: A meta-analysis of six prospective studies of falling in Parkinson's disease. Mov Disord 22: 1892-1900, 2007
31)Lindholm B, Nilsson MH, Hansson O, Hagell P: External validation of a 3-step falls prediction model in mild Parkinson's disease. J Neurol 263: 2462-2469, 2016
32)福武敏夫: Parkinson病の姿勢異常—骨粗鬆症性骨折後の姿勢異常を理解するために. 脊椎脊髄25: 1025-1032, 2012
33)Khlebtovsky A, Djaldetti R, Rodity Y, Keret O, Tsvetov G, et al: Progression of postural changes in Parkinson's disease: quantitative assessment. J Neurol 264: 675-683, 2017
34)Nakane S, Yoshioka M, Oda N, Tani T, Chida K, et al: The characteristics of camptocormia in patients with Parkinson's disease: a large cross-sectional multicenter study in Japan. J Neurol Sci 358: 299-303, 2015
35)亀山 隆: Parkinson病におけるcamptocormiaの発症機序. 脊椎脊髄26: 926, 2013
36)Bloch F, Houeto JL, Tezenas du Montcel ST, Bonneville F, Etchepare F, et al: Parkinson's disease with camptocormia. J Neurol Neurosurg Psychiatry 77: 1223-1228, 2006
37)Tiple D, Fabbrini G, Colosimo C, Ottaviani D, Camerota F, et al: Camptocormia in Parkinson's disease: an epidemiological and clinical study. J Neurol Neurosurg Psychiatry 80: 145-148, 2009
38)Babat LB, McLain RF, Bingaman W, Kalfas I, Young P, et al: Spinal surgery in patients with Parkinson's disease: construct failure and progressive deformity. Spine (Phila Pa 1976) 29: 2006-2012, 2004
39)Jankovic J: Post-traumatic movement disorders: central and peripheral mechanisms. Neurology 44: 2006-2014, 1994
40)Jankovic J: Can peripheral trauma induce dystonia and other movement disorders? Yes! Mov Disord 16: 7-12, 2001
41)Galbusera F, Bassani T, Stucovitz E, Martini C, Aguirre MFI, et al: Surgical treatment of spinal disorders in Parkinson's disease. Eur Spine J 27(Suppl 1): S101-S108, 2018
42)中川幸洋, 吉田宗人: Parkinson病患者における腰椎変性疾患の手術成績. 脊椎脊髄25: 1033-1038, 2012
43)渡辺 慶, 平野 徹, 大橋正幸, 長谷川和宏: Parkinson病に伴う脊柱変形の外科治療. 脊椎脊髄30: 484-490, 2017
44)Baker JF, McClelland S 3rd, Hart RA, Bess RS: Management of spinal conditions in patients with Parkinson's disease. J Am Acad Orthop Surg 25: e157-e165, 2017［doi: 10.5435/JAAOS-D-16-00627］
45)Schroeder JE, Hughes A, Sama A, Weinstein J, Kaplan L, et al: Lumbar spine surgery in patients with Parkinson's disease. J Bone Joint Surg Am 97: 1661-1666, 2015
46)Upadhyaya CD, Starr PA, Mummaneni PV: Spinal deformity and Parkinson's disease: a treatment algorithm. Neurosurg Focus 28: E5, 2010［doi: 10.3171/2010.1.FOCUS09288］
47)Yamato Y, Hasegawa T, Togawa D, Yoshida G, Yasuda T, et al: Extensive spinal fusion surgery in patients with Parkinson's disease or atypical parkinsonism: time course of clinical outcome in 5 years progress report. Spine (Phila Pa 1976) 45: E217-E226, 2020［doi: 10.1097/BRS.0000000000003246］
48)Forestier J, Rotes-Querol J: Senile ankylosing hyperostosis of the spine. Ann Rheum Dis 9: 321-330, 1950
49)Resnick D, Shaul SR, Robins JM: Diffuse idiopathic skeletal hyperostosis (DISH): Forestier's disease with extraspinal manifestations. Radiology 115: 513-524, 1975
50)上井 浩: DISHの定義, 分類, 病因. 脊椎脊髄32: 648-652, 2019
51)Fujimori T, Watabe T, Iwamoto Y, Hamada S, Iwasaki M, et al: Prevalence, concomitance, and distribution of ossification of the spinal ligaments: results of whole spine CT scans in 1500 Japanese patients. Spine (Phila Pa 1976) 41: 1668-1676, 2016
52)Oudkerk SF, de Jong PA, Attrach M, Luijkx T, Buckens CF, et al: Diagnosis of diffuse idiopathic skeletal hyperostosis with chest computed tomography: inter-observer agreement. Eur Radiol 27: 188-194, 2017
53)Kagotani R, Yoshida M, Muraki S, Oka H, Hashizume H, et al: Prevalence of diffuse idiopathic skeletal hyperostosis (DISH) of the whole spine and its association with lumbar spondylosis and knee osteoarthritis: the ROAD study. J Bone Miner Metab 33: 221-229, 2015
54)Hirasawa A, Wakao N, Kamiya M, Takeuchi M, Kawanami K, et al: The prevalence of diffuse idiopathic skeletal hyperostosis in Japan: the first report of measurement by CT and review of the literature. J Orthop Sci 21: 287-290, 2016
55)豊田宏光, 寺井秀富, 山田賢太郎, 中村博亮: DISHの疫学. 脊椎脊髄32: 653-660, 2019
56)Nishimura S, Nagoshi N, Iwanami A, Takeuchi A, Hirai T, et al: Prevalence and distribution of diffuse idiopathic skeletal hyperostosis on whole-spine computed tomography in patients with cervical ossification of the posterior longitudinal ligament: a multicenter study. Clin Spine Surg 31: E460-E465, 2018［doi: 10.1097/BSD.0000000000000701］
57)Verlaan JJ, Boswijk PFE, de Ru JA, Dhert WJA, Oner FC: Diffuse idiopathic skeletal hyperostosis of the cervical spine: an underestimated cause of dysphagia and airway obstruction. Spine J 11: 1058-1067, 2011
58)Egerter AC, Kim ES, Lee DJ, Liu JJ, Cadena G, et al: Dysphagia secondary to anterior osteophytes of the cervical spine. Global Spine J 5: e78-e83, 2015［doi: 10.1055/s-0035-1546954］
59)Kawamura I, Tominaga H, Tanabe F, Yamamoto T, Taniguchi N: Cervical alignment of anterior cervical hyperostosis causing dysphagia. Spine (Phila Pa 1976) 44: E269-E272, 2019［doi: 10.1097/BRS.0000000000002836］
60)安田剛敏, 鈴木賀代, 箭原康人, 渡邉健太, 川口善治: びまん性特発性骨増殖症（DISH）における肋椎関節変化と呼吸機能の関連. 脊椎脊髄32: 661-666, 2019
61)岡田英次朗, 塩野雄太, 渡辺航太, 松本守雄: DISHを合併する椎体骨折の診断と治療. 整・災外62: 581-585, 2019
62)筑田博隆: 高齢者の非骨傷性頸髄損傷. 脊椎脊髄29: 431-436, 2016
63)Maeda T, Ueta T, Mori E, Yugue I, Kawano O, et al: Soft-tissue damage and segmental instability in adult patients with cervical spinal cord injury without major bone injury. Spine (Phila Pa 1976) 37: E1560-E1566, 2012［doi: 10.1097/BRS.0b013e318272f345］
64)Schneider RC, Cherry G, Pantek H: The syndrome of acute central cervical spinal cord injury: with special reference to the mechanisms involved in hyperextension injuries of cervical spine. J Neurosurg 11: 546-577, 1954
65)Chikuda H, Seichi A, Takeshita K, Matsunaga S, Watanabe M, et al: Acute cervical spinal cord injury complicated by preexisting ossification of the posterior longitudinal ligament: a multicenter study. Spine (Phila Pa 1976) 36: 1453-1458, 2011
66)Konomi T, Yasuda A, Fujiyoshi K, Yamane J, Kaneko S, et al: Clinical outcomes of late decompression surgery following cervical spinal cord injury with pre-existing cord compression. Spinal Cord 56: 366-371, 2018
67)Nakashima H, Yukawa Y, Suda K, Yamagata M, Ueta T, et al: Narrow cervical canal in 1211 asymptomatic healthy subjects: the relationship with spinal cord compression on MRI. Eur Spine J 25: 2149-2154, 2016
68)緒方 徹: 高齢者脊髄損傷予防とロコモ対策. 整・災外61: 327-331, 2018
掲載誌情報
