BRAIN and NERVE－神経研究の進歩72巻8号

2020年08月発行

特集 サルコイドーシス

筋サルコイドーシス

著者： 杉江和馬¹

所属機関： ¹奈良県立医科大学脳神経内科学講座

ページ範囲：P.863 - P.870

文献概要

筋サルコイドーシスは，非乾酪性類上皮細胞肉芽腫が筋組織内で免疫学的機序により形成される原因不明の肉芽腫性筋炎である。その多くが無症候性で画像検査や筋生検により発見される。症候性（＝サルコイドミオパチー）は稀な病態で，進行性の筋力低下や筋萎縮を呈する場合があり，早期診断・早期治療が求められる。診断には画像検査とともに丹念な筋病理解析が必須である。ステロイド治療が第1選択であるが，難治例もあり，依然治療方針は確立しておらず今後の課題である。

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