BRAIN and NERVE－神経研究の進歩73巻5号

2021年05月発行

増大特集 中枢神経の自己免疫性・炎症性疾患ハンドブック

第2章　疾患各論

急性散在性脳脊髄炎(ADEM)

著者： 越智博文¹ 加藤丈陽¹²

所属機関： ¹愛媛大学大学院医学系研究科脳神経内科・老年医学講座 ²医療法人かとう内科

ページ範囲：P.466 - P.474

文献概要

急性散在性脳脊髄炎は，多巣性の神経症候が急性ないしは亜急性に出現する中枢神経の炎症性脱髄疾患である。感染やワクチン接種などの先行事象を認めることが多く，免疫介在性疾患と考えられている。主に小児に発症し，通常は単相性であるが，稀に再発し多相性のことがある。急性期治療の第一選択はステロイドパルス治療であり，長期予後はおおむね良好である。

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