BRAIN and NERVE－神経研究の進歩73巻5号

2021年05月発行

増大特集 中枢神経の自己免疫性・炎症性疾患ハンドブック

第2章　疾患各論

抗MOG抗体関連疾患

著者： 藤盛寿一¹ 中島一郎¹

所属機関： ¹東北医科薬科大学医学部老年神経内科学

ページ範囲：P.483 - P.488

文献概要

抗MOG抗体関連疾患は，抗MOG抗体が陽性となり，中枢神経系に炎症性脱髄病変を生じる，近年確立された新しい疾患単位である。病型として視神経炎，脊髄炎，視神経脊髄炎関連疾患，脳幹脳炎，脳炎などを呈する。診断にはCBA法を用いた抗MOG抗体の同定に加えて，脳MRI，髄液検査などによる炎症性脱髄の証明が必要である。急性期治療に加えて，症例ごとに再発予防のための免疫治療を検討することが重要である。

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