BRAIN and NERVE－神経研究の進歩73巻5号

2021年05月発行

増大特集 中枢神経の自己免疫性・炎症性疾患ハンドブック

第2章　疾患各論

傍腫瘍性中枢神経疾患

著者： 木村暁夫¹

所属機関： ¹岐阜大学大学院医学系研究科脳神経内科学分野

ページ範囲：P.620 - P.630

文献概要

傍腫瘍性神経症候群は，悪性腫瘍に対する免疫応答が神経組織を障害することにより生じる神経疾患である。近年新たな抗神経抗体の発見に伴い，患者数の増加が報告されている。また免疫チェックポイント阻害薬は，傍腫瘍性神経症候群を合併しやすい腫瘍に対しても使用される機会が増えており，今後さらなる患者の増加につながる可能性も予想される。本論では，傍腫瘍性中枢神経疾患の病態，診断，治療，予後について概説する。

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